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31 October 1998 (Vol 317, No 7167)
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This week's This week in the BMJ
Terms used to describe trials may have different meanings for patients [Full text] FREE
Two thousand schizophrenia trials, 1948-97---and still much room for improvement [Full text] FREE
Concealed random allocation protects against bias in clinical trials [Full text] FREE
Quality of life is rarely and poorly measured in randomised controlled trials [Full text] FREE
Patient centred care produced greater satisfaction but less knowledge [Full text] FREE

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This week's Editorials

Unbiased, relevant, and reliable assessments in health care
Iain Chalmers
BMJ  1998;317:1167-1168
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Clinical trials in primary care
Robbie Foy, Jayne Parry, Brian McAvoy
BMJ  1998;317:1168-1169
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Trials: the next 50 years
Richard Peto, Colin Baigent
BMJ  1998;317:1170-1171
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Cluster randomised trials: time for improvement
Marion K Campbell, Jeremy M Grimshaw
BMJ  1998;317:1171-1172
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Being a modern pharmaceutical company
Richard Sykes
BMJ  1998;317:1172-1180
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This week's Letters

Protecting children from armed conflict
Derek Summerfield, C D Cooper, David Meddings
BMJ  1998;317:1249
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Randomised controlled trial exists of levonorgestrel intrauterine system for menorrhagia
Amaju Ikomi, Nutan Gupta
BMJ  1998;317:1250
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Clarification of comments on trial of aminosidine in visceral leishmaniasis
P Olliaro, T K Jha
BMJ  1998;317:1250
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Attention deficit hyperactivity disorder in children
David Bramble, Anne Klassen, Parminder Raina, Anton Miller, Shoo Lee, M S Thambirajah, Andrew Weaver, Geoffrey D Kewley
BMJ  1998;317:1250
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Cholestanol and survival with simvastatin
E J Wallis, R Williamson, L E Ramsay, W W Yeo, P R Jackson, Tatu A Miettinen, Helena Gylling, Timo Strandberg, Seppo Sarna
BMJ  1998;317:1252
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Cholesterol lowering diets and coronary heart disease
M F Oliver, Shaun Conway
BMJ  1998;317:1253
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Single dose of anti-D immunoglobulin for antenatal prophylaxis is smaller in the Netherlands than in the United Kingdom
Bob van Dijk
BMJ  1998;317:1253
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EU doctors get caught in training trap
Andrea Perinti
BMJ  1998;317:1254
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This week's News

UK surgeons may undergo performance review every five years
Susan Mayor
BMJ  1998;317:1173
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Expert team to investigate concerns at Scottish hospital
Bryan Christie
BMJ  1998;317:1173
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In brief
BMJ  1998;317:1174
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US abortion doctor shot dead
James Ciment
BMJ  1998;317:1174
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Iceland breast cancer study questions the risk attributable to gene mutations
Vicki Madden
BMJ  1998;317:1174
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Unmatched bone marrow transplants successfully treat leukaemia
Judy Siegel-Itzkovich
BMJ  1998;317:1175
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UK survey shows improved diet in elderly
John Warden
BMJ  1998;317:1175
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UK paediatric surgeon wins libel damages
Clare Dyer
BMJ  1998;317:1175
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US expands prescribing recommendations for aspirin
Deborah Josefson
BMJ  1998;317:1176
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Nurse shortage threatens UK care
Louise McKee
BMJ  1998;317:1176
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Neutron beam therapy targets brain cancer
Zosia Kmietowicz
BMJ  1998;317:1176
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This week's Clinical review

The ethics of randomised controlled trials from the perspectives of patients, the public, and healthcare professionals
Sarah J L Edwards, R J Lilford, J Hewison
BMJ  1998;317:1209-1212
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ABC of oxygen: Assessing and interpreting arterial blood gases and acid-base balance
Adrian J Williams
BMJ  1998;317:1213-1216
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This week's General practice

Randomised controlled trial of patient centred care of diabetes in general practice: impact on current wellbeing and future disease risk
Ann Louise Kinmonth, Alison Woodcock, Simon Griffin, Nicki Spiegal, Michael J Campbell
BMJ  1998;317:1202-1208
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This week's Soundings

Winter draws on
James Owen Drife
BMJ  1998;317:1261
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This week's Personal views

Evaluating new treatments
Lawrence Cranberg
BMJ  1998;317:1261
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This week's Education and debate

Controlled trials: the 1948 watershed
Richard Doll
BMJ  1998;317:1217-1220
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Use of randomisation in the Medical Research Council's clinical trial of streptomycin in pulmonary tuberculosis in the 1940s
Alan Yoshioka
BMJ  1998;317:1220-1223
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Mammography and the politics of randomised controlled trials Commentary: The public has a role to play in translating evidence into practice Commentary: Why are researchers surprised when there is not a smooth transition from research into practice?
Jane Wells, Giok J Ong, Hilda Bastian
BMJ  1998;317:1224-1230
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Marketing medicines through randomised controlled trials: the case of interferon
Toine Pieters
BMJ  1998;317:1231-1233
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"A calculated risk": the Salk polio vaccine field trials of 1954
Marcia Meldrum
BMJ  1998;317:1233-1236
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Efficient management of randomised controlled trials: nature or nurture
Barbara Farrell
BMJ  1998;317:1236-1239
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Experimentation and social interventions: a forgotten but important history
Ann Oakley
BMJ  1998;317:1239-1242
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The controlled clinical trial turns 100 years: Fibiger's trial of serum treatment of diphtheria
Asbjørn Hróbjartsson, Peter C Gøtzsche, Christian Gluud
BMJ  1998;317:1243-1245
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Ovarian ablation in breast cancer, 1896 to 1998: milestones along hierarchy of evidence from case report to Cochrane review
Michael J Clarke
BMJ  1998;317:1246-1248
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This week's VIEWS AND REVIEWS

Bookcase
BMJ  1998;317:1262
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This week's Reviews

Tuberculosis: story of medical failure
Chris Holme
BMJ  1998;317:1260
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BMJ  1998;317:1262
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This week's Fillers

A memorable patient: Never underestimate a placebo
J H Baron
BMJ  1998;317:1190
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A patient to remember: A surfeit of experts
H A Dewar
BMJ  1998;317:1200
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Fifty years ago: The new NHS: The BMA under fire
BMJ  1998;317:1201
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One hundred years ago: Labour and refreshment
BMJ  1998;317:1201
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Endpiece: How to buy gadgets
BMJ  1998;317:1202
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Endpiece: Alternative definitions
BMJ  1998;317:1209
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A memorable patient: The inflating lady
Solomon Almond
BMJ  1998;317:1230
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Words: Nosocomial
Irvine Loudon
BMJ  1998;317:1242
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This week's Corrections

Effects of the Heartbeat Wales programme
BMJ  1998;317:1254
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Cost effectiveness of community leg ulcer clinics
Peter J Franks, Christine J Moffatt
BMJ  1998;317:1254
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Antiretroviral combination therapy and HIV infection
BMJ  1998;317:1254
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This week's Career focus

Urological surgery
Neville Harrison
BMJ  1998;317:2
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Briefing: Recent concern in Britain has centered round the relative unpopularity ...
BMJ  1998;317:3
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Briefing: Student electives may form an important bridge between undergraduate experience ...
BMJ  1998;317:3a
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Briefing: Another of those surveys that looks at the academic achievement ...
BMJ  1998;317:3b
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This week's TBRCT

STREPTOMYCIN IN PULMONARY TUBERCULOSIS (Reprinted from BMJ 1948:ii:790-1)
BMJ  1998;317:1248
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THE CONTROLLED THERAPEUTIC TRIAL (Reprinted from BMJ 1948:ii:791-2)
BMJ  1998;317:1248
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STREPTOMYCIN TREATMENT OF PULMONARY TUBERCULOSIS (Reprinted from BMJ 1948:ii769-782)
BMJ  1998;317:1248
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This week's CHOICE

Fifty years of randomised controlled trials
BMJ  1998;317
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This week's MEDICOPOLITICAL DIGEST

GPs in England will receive advice about PCGs WMA to examine doping in sport BMA warns about cuts to defence medical services Confusion remains over patient packs
BMJ  1998;317:1257
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This week's MEDICINE AND MULTIMEDIA

Randomised Controlled Trials: A User's Guide
John-Paul Vader
BMJ  1998;317:1258
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Choosing between randomised and non-randomised studies: a systematic review
M J Campbell
BMJ  1998;317:1258
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Urinary Disorders and Male Health: A Decision Making Guide for Patients
Trevor Gibbs
BMJ  1998;317:1258
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WEBSITE OF THE WEEK
Douglas Carnall
BMJ  1998;317:1258
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This week's Obituaries

Philip Henry Connell Allan Urquhart Downie Christopher Chilcot Evans John Bonham Carter Evelegh Gustav ("Gus") Julius Fraenkel Desmond Robert Gamble Alexander ("Sanyi") Gellert Beryl Jennie Goff Henry Russell
Thomas Bewley, Stephen Lock, Tim Ashmore, Ann Harden, A G Huff, David Pyke, Elizabeth I Tanner, Vera Somen, Andrew Gellert, Brenda Grimmett, K J Waters, T S Waters
BMJ  1998;317:1255
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This week's Papers

Random allocation or allocation at random? Patients' perspectives of participation in a randomised controlled trial
Katie Featherstone, Jenny L Donovan
BMJ  1998;317:1177-1180
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Content and quality of 2000 controlled trials in schizophrenia over 50 years
Ben Thornley, Clive Adams
BMJ  1998;317:1181-1184
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The unpredictability paradox: review of empirical comparisons of randomised and non-randomised clinical trials
Regina Kunz, Andrew D Oxman
BMJ  1998;317:1185-1190
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Reporting on quality of life in randomised controlled trials: bibliographic study
Caroline Sanders, Matthias Egger, Jenny Donovan, Deborah Tallon, Stephen Frankel
BMJ  1998;317:1191-1194
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Analysis and interpretation of cost data in randomised controlled trials: review of published studies
Julie A Barber, Simon G Thompson
BMJ  1998;317:1195-1200
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A randomised trial of hospital versus home administered enemas for flexible sigmoidoscopy
Jonathan N Lund, Declan Buckley, David Bennett, Charles Maxwell-Armstrong, Andrew Smith, Gillian Tierney, John Scholefield
BMJ  1998;317:1201-1210
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