Releases Saturday 6 November 1999
No 7219 Volume 319

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(1) ANTIBIOTIC PRESCRIBING IN LOCAL COMMUNITIES
IS LINKED TO LOCALIZED RESISTANCE


(1) ANTIBIOTIC PRESCRIBING IN LOCAL COMMUNITIES
IS LINKED TO LOCALIZED RESISTANCE

(Antibiotic prescribing and antibiotic resistance in community
practice: retrospective study, 1996-8)
http://www.bmj.com/cgi/content/full/319/7219/1239

In this week's BMJ a team of researchers from Wales show
for the first time that antibiotic prescribing within geographic
communities can lead to localized antibiotic resistance. Dr John
Magee from the Public Health Laboratory Service along with
colleagues from the University of Wales College of Medicine
and Bro Taf Health Authority report the findings of a two year
study involving patients in North and South Wales. The authors
examined the results of antibiotic sensitivity tests on bacteria in
urine samples that had been taken by general practitioners for
the purposes of diagnosing urinary tract infections.

Magee et al found that the correlation between the prescribing
of certain antibiotics and resistance to those same antibiotics
was often significant. They say that this is the first survey to
suggest such geographically localized effects from antibiotic use
in communities. The authors conclude that their findings "...bring
the debate on prescribing in the community from the national to
the local level and provide preliminary evidence that doctors
may have to face the broader consequences of their antibiotic
prescribing among their own patients."

Contact:

Simon Gregor, Head of Press and Media Activities,
Public Health Laboratory Service Headquarters, Colindale
Avenue, London
Email: sgregor@phls.nhs.uk


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