Releases Saturday 19 August 2000
No 7259 Volume 321

Please remember to credit the BMJ as source when publicising an
article and to tell your readers that they can read its full text on the
journal's web site (http://bmj.com).

If your story is posted on a website please include a link back to
the source BMJ article (URL's are given under titles).


(1) THIRD GENERATION PILLS DO NOT INCREASE
RISK OF VENOUS CLOTTING

(2) TEENAGERS WHO BECOME PREGNANT DO SEEK
CONTRACEPTIVE ADVICE

(3) DOES HOMOEOPATHY HAVE A THERAPEUTIC
EFFECT?

(4) PARENTS NEED HELP TO TELL THEIR CHILDREN
ABOUT CANCER

(5) CHANGES IN PSYCHIATRIC CARE BLAMED FOR
INCREASED DEATHS AMONG SCHIZOPHRENIA
PATIENTS



(1) THIRD GENERATION PILLS DO NOT INCREASE
RISK OF VENOUS CLOTTING

(Effect of 1995 pill scare on rates of venous
thromboembolism among women taking combined oral
contraceptives: analysis of General Practice Research
Database)
http://bmj.com/cgi/content/full/321/7259/477

The newer types of combined oral contraceptive pills do not
put women at increased risk of clots in the veins, contrary to
previous information, a study in the BMJ shows this week.

Since 1995 it has been believed that third generation pills,
which contain gestodene or desogestrel, can cause a twofold
increase in risk of venous clotting compared to older
combined formulations.

The study compared the incidence of venous clots in women
in the three years before and after the 1995 "pill scare" when
use of "third generation" oral contraceptives fell from 54% to
14% in women aged 15-49 taking the pill. Data was taken
from 304 general practices throughout the country that fed
information to a central database. Women who were at risk
of clots for other reasons were not included in the figures.

The results show that although the use of third generation oral
contraceptives fell during the period after 1995, the rates of
venous clots among women taking the pill did not change
significantly.

Contact:

Professor R D T Farmer, Postgraduate Medical School,
University of Surrey, Guildford, Surrey GU2 7DJ
Email: r.farmer@surrey.ac.uk

(2) TEENAGERS WHO BECOME PREGNANT DO SEEK
CONTRACEPTIVE ADVICE

(Paper: Consultation patterns and provision of contraception
in general practice before teenage pregnancy: case-control
study)
http://bmj.com/cgi/content/full/321/7259/486

(Editorial: Never underestimate the force of reproduction)
http://bmj.com/cgi/content/full/321/7259/461

Teenagers who become pregnant are not as reluctant or ill
informed about contraception as previously assumed. Most
teenagers who become pregnant have discussed
contraception with a health professional in the year before
conception, according to a study in this week's BMJ.

Looking at 240 cases of teenage pregnancy in 14 general
practices in the Trent region, the study found that 71% of
teenagers had discussed contraception with a health
professional, and 50% had been prescribed regular oral
contraception. In the 22% of cases resulting in termination,
teenagers were more likely to have received emergency
rather than regular oral contraception in this year. Overall,
compared to others of their age, teenagers who became
pregnant were found to consult their GP more often, both
about contraception and unrelated matters.

The study shows that teenagers who become pregnant are
not as reluctant or ill informed about contraception as
previously assumed. The authors emphasise a need for
adequate follow-up of teenagers receiving emergency
contraception.

In an accompanying editorial, Professor Basil Donovan of the
University of Sydney seeks to explain these findings. He
suggests that teenagers may not be getting the most out of
their consultations due to time pressures, their own
embarrassment, or lack of rapport. Use of oral contraception
in this age group is often sporadic and therefore ineffective.
This warrants consideration of more permanent reversible
methods of contraception.

Contacts:

[Paper] R Churchill, Clinical Lecturer, Division of General
Practice, University of Nottingham Medical School, Queen's
Medical Centre, Nottingham NG7 2UH
Email: dick.churchill@nottingham.ac.uk

[Editorial] Basil Donovan, Clinical Professor, Department of
Public Health and Community Medicine, University of
Sydney, Sydney Hospital, Sydney NSW, Australia
Email: donovanb@sesahs.nsw.gov.au

(3) DOES HOMOEOPATHY HAVE A THERAPEUTIC
EFFECT?

(Paper: Randomised controlled trial of homoeopathy versus
placebo in perennial allergic rhinitis with overview of four trial
series)
http://bmj.com/cgi/content/full/321/7259/471

(Commentary: Larger trials are needed)
http://bmj.com/cgi/content/full/321/7259/471#resp1

Much scepticism exists about the effectiveness of
homoeopathy, but the time may have come to confront the
idea that homoeopathic treatment differs from placebo - a
chemically inert substance given in place of a drug -
according a new study published in this week's BMJ.

Researchers in Glasgow randomly treated 50 patients
suffering from nasal allergies with either a homoeopathic
preparation or placebo. Each day, for four weeks, patients
measured their nasal air flow and recorded symptoms such as
blocked, runny or itchy nose, sneezing and eye irritation. Both
groups reported improvement in symptoms but, on average,
patients who received homoeopathy had significantly greater
improvement in nasal air flow - 28% compared with 3%
among those in the placebo group.

Recent attempts to resolve the controversy surrounding
homoeopathy have resulted in over 180 clinical trials to date.
Against this background, and combined with results of three
similar studies, these findings further strengthen the evidence
that homoeopathy shows some therapeutic effect over
placebo, say the authors.

In an accompanying commentary, Tim Lancaster at the
Institute of Health Sciences in Oxford and Andrew Vickers at
the Sloane-Kettering Cancer Centre in New York emphasise
the importance of high quality randomised trials in the
evaluation of homoeopathy. They suggest that the new
challenge "is to do the large trials that really could change
thinking."

Contacts:

[Paper] David Reilly, Academic Departments, Glasgow
Homoeopathic Hospital, Glasgow G12 0XQ
Email: davidreilly1@compuserve.com

[Commentary] Tim Lancaster, Clinical Reader in General
Practice, Department of Primary Health Care, Institute of
Health Sciences, Oxford OX3 7LF
Email: tim.lancaster@public-health.oxford.ac.uk

(4) PARENTS NEED HELP TO TELL THEIR CHILDREN
ABOUT CANCER

(Paper: Qualitative interview study of communication
between parents and children about maternal breast cancer)
http://bmj.com/cgi/content/full/321/7259/479

(Editorial: Telling children about a parent's cancer)
http://bmj.com/cgi/content/full/321/7259/462

Most parents diagnosed with cancer avoid communicating
with their children in the hope of preventing distress. Yet a
paper in this week's BMJ suggests that parents need help to
think about how they might talk to their children and how to
deal with their reactions.

Jacqueline Barnes and colleagues interviewed 32 mothers of
56 school age children, recently diagnosed with breast
cancer, to explore why parents do or do not talk to their
children about their illness and what help parents have
received or might have liked. They found that women were
most likely to begin talking to their children once a definite
diagnosis was made, but a fifth of children had still not been
told that their mother was ill at the stage of surgery. The most
common reasons for not communicating was to avoid facing
questions about cancer and death and preventing children's
distress. One mother of a 9 year old stated: "He'll say
±you've got cancer, are you going to die?" Another said: "I
feel if I mentioned it to him he would just worry so much."

Only a minority of mothers had been offered any kind of help
with breaking bad news to their children, say the authors.
More support is needed to help parents think about whether,
what and how to tell their children to avoid unnecessary
anxiety within the family, they conclude.

In an accompanying editorial, Duncan Keeley, a general
practitioner in Oxfordshire, emphasises the importance of
talking to children about painful events, saying "that it is better
to talk badly about things than not to talk about them at all."
He suggests that general practitioners should be prepared to
assist parents in helping their children to understand difficult
or painful truths.

Contact:

[Editorial] Duncan Keeley, General Practitioner, The Health
Centre, Thame, Oxfordshire OX9 3JZ

(5) CHANGES IN PSYCHIATRIC CARE BLAMED FOR
INCREASED DEATHS AMONG SCHIZOPHRENIA
PATIENTS

(Time trends in schizophrenia mortality in Stockholm County,
Sweden: cohort study)
http://bmj.com/cgi/content/full/321/7259/483

Increased death rates among patients with schizophrenia are
most probably due to fundamental changes in psychiatric care
and a reduction in hospital beds, says a study in this week's
BMJ.

Researchers in Sweden investigated the date and cause of
death among residents of Stockholm County who had been
diagnosed with schizophrenia between 1976 and 1995.
Overall, they found that death rates had increased 1.7-fold in
men and 1.3-fold in women. Deaths from natural and
cardiovascular causes increased 4.7-fold in men and 2.7-fold
in women; suicide increased 1.6-fold in men and 1.9-fold in
women and deaths from unspecified violence increased
3.8-fold in men and 3.4-fold in women.

During the study period, there were important changes in
psychiatric care offered to patients with schizophrenia, say
the authors. For instance, outpatient treatment replaced long
term patient care and, between 1976 and 1994, hospital
beds available for patients with schizophrenia fell by 64%.
This, suggest the authors, is the most probable explanation for
the rising mortality and emphasises the importance of
monitoring trends in patient groups as indicators of outcome
and quality of psychiatric and medical care.

Contact:

Urban sby, Consultant, Department of Clinical Neuroscience,
Karolinska Institute, S-171 76
Email: Urban.sby@nvso.sll.se


FOR ACCREDITED JOURNALISTS

Embargoed press releases and articles are available from:

Public Affairs Division
BMA House
Tavistock Square
London WC1H 9JR
(contact: pressoffice@bma.org.uk)

and from:

the EurekAlert website, run by the American Association for the
Advancement of Science
(http://www.eurekalert.org)