Releases Saturday 16 December 2000
No 7275 Volume 321

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(1)  WITNESSING TESTS FOR BRAIN STEM DEATH MAY
HELP RELATIVES COPE WITH THEIR LOSS

(2)  EPIDURAL OR SPINAL ANAESTHESIA REDUCES
MAJOR POSTOPERATIVE COMPLICATIONS

(3)  A NEW APPROACH FOR DETECTING HIGH
CHOLESTEROL IN FAMILIES

(4)  EMERGENCY DEPARTMENTS CAN HELP TACKLE
COMMUNITY VIOLENCE

(5)  HIGH RATES OF CAESAREAN SECTION IN CHILE DO
NOT REFLECT PATIENT CHOICE

(6)  SHOULD DOCTORS BE ADVISING YOUNG PEOPLE
TO ABSTAIN FROM SEX?
 



(1)  WITNESSING TESTS FOR BRAIN STEM DEATH MAY
HELP RELATIVES COPE WITH THEIR LOSS

(Presence of relatives during testing for brain stem death:
questionnaire study)
http://bmj.com/cgi/content/full/321/7275/1505

The majority of health care professionals involved in testing for
brain stem death believe that allowing relatives to be present
during testing may help them to understand that death has
occurred and may assist the grieving process, finds a study in
this week's BMJ.

Bonner and colleagues surveyed 147 consultants and 167
senior nurses in neurotrauma intensive care units. Although
only 37 consultants and 54 senior nurses had experience of
relatives being present during testing for brain stem death, two
thirds (69%) felt that this was helpful for relatives and 48%
thought that relatives may also gain comfort from being
present. However, major potential problems such as spinal
reflexes (85%) and dealing with relatives' distress (70%) must
be anticipated. Forty-five per cent of respondents said they
would be more willing to allow the presence of relatives if
adequate support was available.

At present, a minority of doctors and nurses invite relatives to
observe testing for brain stem death. More may consider doing
so in the future. However, it remains to be seen whether
allowing relatives to observe testing is beneficial, and the
associated problems should not be underestimated, conclude
the authors.

Contact:

Stephen Bonner, Consultant, Intensive Care Unit, South
Cleveland Hospital, Middlesbrough, UK
Email:  Steve.Bonner{at}btinternet.com
 

(2)  EPIDURAL OR SPINAL ANAESTHESIA REDUCES
MAJOR POSTOPERATIVE COMPLICATIONS

(Reduction in postoperative mortality and morbidity with
epidural or spinal anaesthesia: results from overview of
randomised trials)
http://bmj.com/cgi/content/full/321/7275/1493

Giving patients epidural or spinal anaesthesia (known as
neuraxial blockade) during major surgery reduces mortality by
about a third and also reduces the risk of serious postoperative
complications in a wide range of patient groups, finds a study in
this week's BMJ.

Rodgers and colleagues analysed 141 trials, involving over
9,500 patients, to provide more reliable estimates of the effects
of neuraxial blockade. In patients receiving neuraxial blockade,
overall mortality was reduced by about a third. Neuraxial
blockade also approximately reduced the odds of deep vein
thrombosis by 44%, pulmonary embolism by 55%, transfusion
requirements by 50%, pneumonia by 39%, and respiratory
depression by 59%. There were also reductions in heart attack
and kidney failure. Furthermore, the benefits did not differ by
the type of surgical group, the type of neuraxial blockade
(epidural or spinal), or in trials where neuraxial blockade was
combined with general anaesthesia, add the authors.

The size of some of these benefits remains uncertain, and
further research is required to determine whether these effects
are due solely to benefits of neuraxial blockade or partly to
avoidance of general anaesthesia, say the authors. However,
given that the risks of fatal or life threatening events are
increased several fold after major surgery, these findings
support more widespread use of neuraxial blockade, they
conclude.

Contacts:

Anthony Rodgers, Clinical Trials Research Unit, Division of
Medicine, The University of Auckland, New Zealand
Email: a.rodgers{at}ctru.aukland.ac.nz

or

Stephen Schug, Division of Anaesthesiology , The University
of Auckland, New Zealand
Email:  s.schug{at}auckland.ac.nz
 

(3)  A NEW APPROACH FOR DETECTING HIGH
CHOLESTEROL IN FAMILIES

(Outcome of case finding among relatives of patients with
known heterozygous familial hypercholesterolaemia)
http://bmj.com/cgi/content/full/321/7275/1497

(Editorial: Screening for familial hypercholesterolaemia)
http://bmj.com/cgi/content/full/321/7275/1483

A nurse-led genetic register, linking lipid clinics nationally, may
be a more effective way of detecting new patients with a
family history of high cholesterol than general population
screening, suggests a study in this week's BMJ.

Two-hundred first degree relatives of known patients with a
family history of high cholesterol were given cholesterol tests
by nurses in two lipid clinics in Manchester. The screening
yielded 121 newly detected patients with a family history of
high cholesterol and most were diagnosed before evidence of
coronary heart disease was apparent. Because 1 in 500 people
in Europe and North America are affected by this condition, to
detect a similar number by population screening over 60,000
tests would have been required. Furthermore, general
screening would have failed to identify most of these patients
because testing is restricted to those with other risk factors for
coronary heart disease - such as high blood pressure and
diabetes - which were uncommon in the newly diagnosed
patients, explain the authors.

Given the high death rate associated with a first heart attack
(around 30%) detecting new cases before evidence of
coronary heart disease is apparent is one important benefit of
this method, say the authors. Indeed, there are many potential
advantages of detecting new patients with a family history of
high cholesterol through established lipid clinics using the
genetic register approach reported in this study, they conclude.

Contact:

Professor Paul Durrington, University of Manchester,
Department of Medicine, Manchester Royal Infirmary, UK
Email: pdurrington{at}hq.cmht.nwest.nhs.uk
 

(4)  EMERGENCY DEPARTMENTS CAN HELP TACKLE
COMMUNITY VIOLENCE

(Using injury data for violence prevention)
http://bmj.com/cgi/content/full/321/7275/1481

Injury data derived from hospital emergency departments will
be shared with the police as part of new government proposals
to help tackle community violence. In this week's BMJ
Jonathan Shepherd and colleagues look at how a medical
perspective of violence, combined with the traditional police
perspective, has already begun to reap rich rewards.

In the UK only about 25% to 50% of offences which lead to
treatment in emergency departments appear in police records.
Yet recording injuries treated in emergency departments has
the potential for largely complete coverage of serious
community violence and provides local information of
importance to the police that will help them respond.

A recent pilot scheme in Cardiff, South Wales - giving
emergency departments opportunities to share non-confidential
data with the police and local authority - has focused policing
on local violence hotspots, such as bars, nightclubs and public
streets. As well as helping locally, this approach has identified
and led to modifications of one of the most commonly used
weapons in assaults in the UK - bar glasses.

Recent high profile cases of serious community violence
emphasise that health care is often the only public service
which knows about many violent offences, say the authors. If
based on a sound ethical framework to protect the interests of
patients, this approach should help to reduce the burden on
emergency departments and is a rational step towards safer
and more just communities, they conclude.

Contact:

Jonathan Shepherd, Professor of Oral and Maxillofacial
Surgery, University of Wales College of Medicine, Cardiff, UK
Email: shepherdjp{at}cardiff.ac.uk
 

(5)  HIGH RATES OF CAESAREAN SECTION IN CHILE DO
NOT REFLECT PATIENT CHOICE

(Relation between private health insurance and high rates of
caesarean section in Chile: qualitative and quantitative study)
http://bmj.com/cgi/content/full/321/7275/1501

In Chile, the rate of caesarean sections in women with private
health insurance is double that of those in the public sector, yet
this does not reflect patients' choice, according to a study in
this week's BMJ.

Between 1995 and 1997, Susan Murray of University College
London studied the day to day organisation, norms and
relationships in private sector maternity care in Santiago, Chile,
to examine the link between private health insurance ? which
has been promoted in Chile since the 1980s ? and high rates of
caesarean section.

Women with private obstetricians showed consistently higher
rates of caesarean section than those cared for by midwives or
doctors on duty in public or university hospitals. However, only
a minority of women receiving private care reported that they
had wanted this method of delivery.

Private health insurers require an obstetrician, rather than a
midwife, to be the primary care provider. The need to provide
such a high level of personalised care often conflicts with the
demanding work schedules of obstetricians who take on
private work to increase their incomes. As a result, the
"programming" (or scheduling) of births by induction of labour
or elective caesarean is a common time management strategy,
says the author. Indeed, the study found that elective
caesarean section is more common in women with private
obstetricians (30-68%) than women not attended by a private
obstetrician (12-14%).

Policies on healthcare financing can influence maternity care
management and outcomes in unforseen ways, says the
author. The prevailing business ethos in health care encourages
such pragmatism among those doctors who do not have a
moral objection to non-medical caesarean section.

Contact:

Susan Murray, Lecturer, Centre for International Child Health,
Institute of Child Health, University College London, UK
Email:  s.murray{at}ich.ucl.ac.uk
 

(6)  SHOULD DOCTORS BE ADVISING YOUNG PEOPLE
TO ABSTAIN FROM SEX?

(For and against: Doctors should advise adolescents to abstain
from sex)
http://bmj.com/cgi/content/full/321/7275/1520

Against a background of high rates of teenage conceptions and
an increasing level of sexually transmitted infections, a debate
in this week's BMJ considers whether advising abstinence is
an effective response to declining teenage sexual health.

Abstinence makes sense and is effective, argues Trevor
Stammers, a tutor in general practice and an author and
broadcaster on sexual health. Research shows that early
intercourse carries greater risks and often leads to subsequent
regret. Sexually active teenagers are also more likely to be
emotionally hurt and have an increased risk of depression and
suicide. Abstinence programmes from the US also show "a
sharp reduction in the number of pregnancies."

Easier availability of contraception and more explicit sex
education at an earlier age are tired and inadequate responses
to declining teenage sexual health, says the author. Doctors
should encourage adolescents to avoid early sexual intercourse
so that they can enjoy better long term sexual health, he
concludes.

Roger Ingham, a researcher on sexual conduct and sex
education, believes that the answer lies in promoting greater
openness about young people's sexuality. A policy of advising
young people not to have sex will not encourage them to deal
with issues such as peer group pressure. It also runs the risk
that they will become even more alienated from adults and that
they will be less likely to use the services available, argues the
author. Indeed, countries such as Norway, Sweden and the
Netherlands - where teenage conception rates are
considerably lower than in the UK - have an earlier and more
open approach to sexual issues in schools and families.

Although poor sexual health among young people is a complex
issue, many people in the UK are making efforts to improve
the sexual health of young people by teaching about
responsibility and good personal relationships, he concludes.

Contacts:

Trevor Stammers, Church Lane Practice, London, UK
Email: stammtg{at}globalnet.co.uk

Roger Ingham, Centre for Sexual Health Research, University
of Southampton, UK
Email: ri{at}soton.ac.uk
 


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