Releases Saturday 17 March 2001
No 7287 Volume 322

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(1)  DURATION OF BREAST FEEDING MAY INFLUENCE
HEALTH IN LATER LIFE

(2)  VIAGRA PASSES INITIAL SAFETY TEST, BUT MORE
RESEARCH IS NEEDED

(3)  SOCIAL DEPRIVATION LINKED TO INCREASED RISK
OF BLINDNESS FROM GLAUCOMA

(4)  PRIVATISATION CAN AFFECT HEALTH



 

(1)  DURATION OF BREAST FEEDING MAY INFLUENCE
HEALTH IN LATER LIFE

(Duration of breast feeding and arterial distensibility in early adult
life: population based study)
http://bmj.com/cgi/content/full/322/7287/643

(Editorial: Does the duration of breast feeding matter?)
http://bmj.com/cgi/content/full/322/7287/625

Breast feeding in infancy is related to reduced arterial function 20
years later, finds a study in this week's BMJ. Although breast
feeding should continue to be recommended to promote infant
health, these findings raise an important question about the
optimal duration of breast feeding.

Leeson and colleagues measured arterial distensibility (a marker
of early cardiovascular disease) in 331 young adults. They found
a greater "stiffness" of the artery wall in those who were breast
fed for four months or more compared with those who were
breast fed for less than four months or exclusively bottle fed.

At this stage, our findings should not influence current advice on
the importance of breast feeding, stress the authors. Even if
prolonged breast feeding were confirmed to have disadvantages,
these would need to be carefully weighed against the advantages.
Further work is needed to explore the optimal duration of breast
feeding in relation to cardiovascular health in later life, they
conclude.

Although the superiority of breast feeding remains unchallenged,
it may eventually become necessary to reappraise the view that
breast feeding is currently recommended for "as long as is
mutually desired" writes Ian Booth, Professor of Paediatrics and
Child Health, in an accompanying editorial. "Independent
corroboration in different populations is required before the
potential impact of these observations can be assessed," he says.

Contacts:

[Paper]: C P M Leeson, Research Fellow, Medical Research
Council Childhood Nutrition Research Centre, Institute of Child
Health, London, UK
Email:  cpm_leeson{at}hotmail.com

[Editorial]: Ian Booth, Professor of Paediatrics and Child Health,
University of Birmingham, UK
Email:  i.w.booth{at}bham.ac.uk
 

(2)  VIAGRA PASSES INITIAL SAFETY TEST, BUT MORE
RESEARCH IS NEEDED

(Cardiovascular events in users of sildenafil: results from first
phase of prescription event monitoring in England)
http://bmj.com/cgi/content/full/322/7287/651

A study in this week's BMJ finds no evidence for a higher
incidence of fatal heart attack or ischaemic heart disease among
English men taking sildenafil (Viagra). Although reassuring,
further evidence is needed to confirm these findings, report the
authors.

Users of sildenafil were identified from NHS prescriptions in
England. Simple questionnaires were posted to the prescribing
general practitioners about five months after the first prescription,
requesting details of events after the drug had been prescribed.

Of 5,601 questionnaires analysed, ten fatal events from
ischaemic heart disease (6 heart attacks and 4 ischaemic heart
disease deaths) were reported. When compared with death rates
in the general population of England in 1998, there was no
evidence for a higher incidence of mortality in this group.

Though the results are reassuring, it is inappropriate to accept
these comparisons as definitive evidence of equivalence between
this cohort of sildenafil users and men in the general population in
England, say the authors. This hypothesis needs to be examined
further, they conclude.

Contact:

Saad Shakir, Director, Drug Safety Research Unit, Bursledon
Hall, Southampton, UK
Email:  saad.shakir{at}dsru.org
 

(3)  SOCIAL DEPRIVATION LINKED TO INCREASED RISK
OF BLINDNESS FROM GLAUCOMA

(Deprivation and late presentation of glaucoma: case-control
study)
http://bmj.com/cgi/content/full/322/7287/639

People with the least material and psychosocial resources seem
to be at greatest risk of going blind from glaucoma, finds a study
in this week's BMJ. This study has important implications for
government policy aimed at reducing social inequalities in health.

Researchers at University College London measured the
socioeconomic status of 220 patients newly diagnosed with
glaucoma at three hospitals in England. Patients who presented
with advanced glaucoma (late presenters) were of lower
occupational status, and lower educational level, were less likely
to have access to a car, and more likely to be tenants. Since
existing evidence shows that late presentation is an important risk
factor for subsequent blindness, these results suggest that
deprived groups are at greater risk of going blind from glaucoma,
explain the authors.

Access to and use of health services are undoubtedly important
factors, say the authors. In addition, long term deprivation may
lead to more rapidly progressive and aggressive disease, add the
authors. "Glaucoma should be included among conditions
targeted in policy aimed at reducing social inequalities in health,"
they conclude.

Contact:

Eric Brunner, Senior Lecturer, Department of Epidemiology and
Public Health, University College London, UK
Email:  e.brunner{at}ucl.ac.uk
 

(4)  PRIVATISATION CAN AFFECT HEALTH

(Employment status and health after privatisation in white collar
civil servants: prospective cohort study)
http://bmj.com/cgi/content/full/322/7287/647

A study in this week's BMJ finds that loss of secure public sector
employment through privatisation has a direct effect on minor
psychiatric illness and longstanding health.

Over 600 employees of one civil service department that was
sold to the private sector were surveyed to examine the health
implications of job loss and re-employment. In general, illness
was greater among those insecurely re-employed or unemployed
than among those securely re-employed.

Insecure re-employment and unemployment was associated with
an increase in minor psychiatric illness compared with people
whose new employment was secure. In addition to this increase
in individual illness, explain the authors, the loss of secure public
sector employment adds to NHS costs through increased
consultations with a general practitioner. This is possibly due to
the increased minor psychiatric illness associated with
privatisation, they conclude.

Contact:

Jane Ferrie, Senior Research Fellow, International Centre for
Health and Society, University College London Medical School,
UK
Email: j.ferrie{at}public-health.ucl.ac.uk
 


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