Releases Saturday 19 May 2001
No 7296 Volume 322

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(1)  SMALLER PACKS OF ANALGESICS HAVE
REDUCED OVERDOSE DEATHS

(2)  MOST PATIENTS CAN BE TREATED SAFELY AT
HOME FOR DEEP VEIN THROMBOSIS

(3)  PATIENT INFORMATION BOOKLETS FAIL TO
REDUCE CONSULTATION RATES

(4)  BMJ EDITOR RESIGNS AFTER UNIVERSITY
ACCEPTS TOBACCO MONEY


 

(1)  SMALLER PACKS OF ANALGESICS HAVE
REDUCED OVERDOSE DEATHS

(Effects of legislation restricting pack sizes of paracetamol
and salicylate on self poisoning in the United Kingdom:
before and after study)
http://bmj.com/cgi/content/full/322/7296/1203

The number of deaths from self poisoning with
paracetamol and salicylates has decreased significantly
since legislation limiting the number of tablets per pack
was introduced in the United Kingdom in 1998, finds a
study in this week's BMJ.

Data including drug related deaths, cases of liver
poisoning, numbers of liver transplantations, and sales
data, were used to assess the impact of the legislation. The
number of tablets in packets of paracetamol and salicylate
preparations decreased markedly in the 12 months after
the legislation. The annual number of deaths from
paracetamol poisoning decreased by 21% and the number
from salicylates decreased by 48%.

There was also a decrease in the number of liver
transplants and admission to liver units with paracetamol
poisoning, and in the number of overdoses of paracetamol
and salicylates in which large numbers of tablets were
taken.

The legislation has been relatively successful, say the
authors, with the results indicating that the main factor was
the reduction in the number of tablets per pack. An even
smaller maximum pack size for pharmacy sales might have
had a greater impact still, they conclude.

Contact:

Keith Hawton, Professor of Psychiatry, Centre for Suicide
Research, Warneford Hospital, Oxford, UK
Email: keith.hawton{at}psych.ox.ac.uk
 

(2)  MOST PATIENTS CAN BE TREATED SAFELY AT
HOME FOR DEEP VEIN THROMBOSIS

(Eligibility for home treatment of deep vein thrombosis:
prospective study)
http://bmj.com/cgi/content/full/322/7296/1212

(Editorial: Routine home treatment of deep vein
thrombosis)
http://bmj.com/cgi/content/full/322/7296/1192

New, effective therapies for acute deep vein thrombosis
mean that most patients do not need to be admitted to
hospital, according to a study in this week's BMJ. These
results challenge the traditional notion that these patients
must be treated in hospital and adds to the evidence that
home treatment of deep vein thrombosis is now routinely
feasible.

Between November 1998 and August 1999, 117
outpatients presenting to the vascular diagnostics unit of
the University Hospital Dresden in Germany were
diagnosed as having acute deep vein thrombosis. Of these,
92 received home treatment ? that is, they were not
admitted at all. Those who did require admission
depended mainly on factors to do with infrastructure
rather than medical reasons, say the authors, and no
serious complications were noted in patients treated at
home.

However, several caveats must be borne in mind when
applying these results to everyday practice, warn
consultant haematologists, John Eikelboom and Ross
Baker, in an accompanying editorial. For instance,
successful home treatment requires adequate resources to
enable rapid clinical assessment, diagnostic testing and
home support when needed. They also point out the need
for education of patients undergoing home treatment and
call for routine monitoring of the safety and effectiveness
of home treatment programmes in individual centres.

Contacts:

[Paper]: Thomas Schwarz, Clinical Research Fellow,
Division of Vascular Medicine, University Hospital,
Dresden, Germany
Email: tho_schwarz{at}hotmail.com

[Editorial]: John Eikelboom, Consultant Haematologist,
Department of Haematology, Royal Perth Hospital, Perth,
Australia
Email:  john.eikelboom{at}health.wa.gov.au
 

(3)  PATIENT INFORMATION BOOKLETS FAIL TO
REDUCE CONSULTATION RATES

(Randomised controlled trial of self management leaflets
and booklets for minor illness provided by post)
http://bmj.com/cgi/content/full/322/7296/1214

(Assessment of impact of information booklets on use of
healthcare services: randomised controlled trial)
http://bmj.com/cgi/content/full/322/7296/1218

(Editorial: Written information for treating minor illness)
http://bmj.com/cgi/content/full/322/7296/1193

Widespread distribution of information booklets on minor
illness is unlikely to reduce demand for health services and
therefore may have a limited role in the National Health
Service, conclude two studies in this week's BMJ.

The first study included almost 4,000 patients in England
who were sent either a booklet with information on 40
common health problems (entitled 'What should I do'), a
summary card covering mainly respiratory illness, or a
leaflet giving the surgery times and how to contact the
doctor in an emergency. Most patients found the
information useful, and it helped their confidence in
managing illness. A small reduction in the number of
doctor-patient contacts in those receiving information
booklets and leaflets was found, but the effect on overall
contacts was not significant. "This raises important
questions about whether such booklets provide sufficient
benefit to justify the use of NHS funds," conclude the
authors.

The second study involved nearly 10,000 patients in
Scotland who were sent either the 'What should I do'
booklet, a health care manual covering 50 common health
problems, or nothing. Again, receipt of either booklet had
no significant effect on health service use. The authors
conclude: "If reduction in demand for services is the aim,
then more sophisticated interventions are required which
build on the available evidence surrounding patient
behaviour."

Such studies are welcome because, although leaflets are
widely used, there is little evidence about their usefulness,
writes primary care specialist, Dr Fitzmaurice, in an
accompanying editorial. But he is not surprised by their
findings. He believes that written material, when given
within the context of a consultation, may be useful as part
of a multifaceted approach to modifying health seeking
behaviour.

Contacts:

[Paper 1]: Paul Little, MRC Clinician Scientist, Primary
Medical Care Group, Aldermoor Health Centre,
Southampton, UK
Email:  psl3{at}soton.ac.uk

[Paper 2]: David Heaney, Research Fellow, Department
of Community Health Sciences, University of Edinburgh,
Edinburgh, UK
Email:  david.heaney{at}ed.ac.uk

[Editorial]: D A Fitzmaurice, Senior Lecturer, Department
of Primary Care and General Practice, University of
Birmingham Medical School, Birmingham, UK
Email: D.A.Fitzmaurice{at}bham.ac.uk
 

(4)  BMJ EDITOR RESIGNS AFTER UNIVERSITY
ACCEPTS TOBACCO MONEY

(News: Editor resigns from post after tobacco gift)
http://bmj.com/cgi/content/full/322/7296/1200/e

Dr Richard Smith, editor of the BMJ, has resigned from
his position as professor of medical journalism at the
University of Nottingham, following its acceptance of
£3.8m from British American Tobacco (BAT) to fund an
international centre for the study of corporate social
responsibility.

The decision was made by readers, who were asked to
vote on bmj.com whether the university should return the
money and whether Dr Smith should resign as professor
of medical journalism if it didn't.

Of 1075 people who voted online during 4-10 May, 84%
were in favour of the university returning the money and
54% felt that Dr Smith should resign if it refused.

In a letter to Sir Colin Campbell, the university's vice
chancellor, Dr Smith describes the university's acceptance
of the money as "a serious mistake and has damaged the
university." He explains that the reason the vote on
whether he should resign was much closer than the vote
on returning the money was "because people were divided
over whether I should dissociate myself from the
University or stay in position and argue my case."

"I am resigning both because I said that I would do what
the BMJ's readers said I should do and because I've
argued so strongly that the University shouldn't have taken
this money," he writes.

A full copy of the letter will be available on bmj.com at
00:01 hours, Friday 18 May 2001 (UK time).

Contact:

Richard Smith, Editor, BMJ, BMA House,
London, UK (via Emma Wilkinson, Press Officer)
Email: ewilkinson{at}bmj.com
 


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