Releases Saturday 11 August 2001
No 7308 Volume 323

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(1)  IQ LINKED TO BIRTH WEIGHT EVEN AMONG
CHILDREN OF NORMAL BIRTH WEIGHT

(2)  UNITED KINGDOM RANKED 24th IN HEALTH
SYSTEMS OF THE WORLD

(3)  STUDY RAISES CONCERNS OVER PUBLICATION
OF UNETHICAL RESEARCH

(4)  SINGLEHANDED DOCTORS ARE NOT
UNDERPERFORMING


(1)  IQ LINKED TO BIRTH WEIGHT EVEN AMONG
CHILDREN OF NORMAL BIRTH WEIGHT

(Influence of variation in birth weight within normal range and
within sibships on IQ at age 7 years: cohort study)
http://bmj.com/cgi/content/full/323/7308/310

Many studies have shown that low birthweight babies have
lower IQ test scores at school age, but a study in this week's
BMJ finds that the association between birthweight and
childhood IQ also applies to children in the normal range of
birth weight.

Researchers at Columbia University, and the New York
Academy of Medicine examined the relation between birth
weight and measured intelligence at age 7 years in over 3000
children, most of whom had birthweight in the normal range
(2500 grams and above).

They found that, on average, IQ at age 7 years was directly
related to birth weight among these children, even after factors
such as mother's age, race, education and socioeconomic
status were taken into account.

The association was stronger in boys than girls. For example,
a 1000g increase in birth weight related to a 4.6 increase in IQ
among boys but only 2.8 points in girls. Unlike most previous
studies of this relationship, the authors also assessed this
association within sibling pairs, eliminating the possible effect
of social and economic differences between families. IQ was
associated with differences in birth weight between boy sibling
pairs but not girls.

These findings may have important implications for future
research on the connections between fetal growth and brain
development, conclude the authors.

Contact:

Thomas Matte, Senior Epidemiologist, Center for Urban
Epidemiologic Studies, New York Academy of Medicine,
New York, USA
Email:  tmatte{at}nyam.org
 

(2)  UNITED KINGDOM RANKED 24th IN HEALTH
SYSTEMS OF THE WORLD

(Comparative efficiency of national health systems: cross
national econometric analysis)
http://bmj.com/cgi/content/full/323/7308/307

(Editorial: Measuring the efficiency of health systems)
http://bmj.com/cgi/content/full/323/7308/295

Countries with the best levels of health do not always have
efficient health systems, according to a study in this week's
BMJ, which ranks the health systems of the world according
to their efficiency in turning expenditure into health. The United
Kingdom is ranked 24th out of 191 countries.

Researchers at the World Health Organisation estimated the
efficiency of health systems in 191 countries, using data from
1993-1997. After taking account of the level of education in
the population, they then ranked the health systems of each
country according to their efficiency in turning expenditure into
health.

Estimated efficiency varied from nearly fully efficient to nearly
fully inefficient, implying that although some countries may be
close to their potential, others are not reaching anywhere near
maximum levels of health, explain the authors.

Oman is ranked first, perhaps because it has drastically
reduced child mortality over the past 40 years, say the
authors. Many other countries performing best are
characterised by "Mediterranean" diets, reinforcing the idea
that many different factors affect health. The United Kingdom
is ranked 24th.

Countries with a history of civil conflict or high prevalence of
HIV and AIDS were less efficient. Performance sharply
increased with health expenditure per capita.

Increasing the resources for health systems is critical to
improving health in poor countries, but important gains can be
made in most countries by using existing resources more
efficiently, they conclude.

Despite its many limitations, the report has achieved
something, argues Professor Martin McKee in an
accompanying editorial. It has exhorted governments to take a
much more active role in promoting health. It has provided a
useful conceptual framework that begins to tease out the goals
of health systems, and it has emphasised the need for a much
better understanding of the undoubted impact that health
systems have on health.

It has not, however, provided a valid answer to the question
of whether one system is better than another, he concludes.

Contacts:

[Paper]: David Evans, Global Programme on Evidence for
Health Policy, World Health Organisation, Geneva,
Switzerland
Email: evansd{at}who.int

[Editorial]: Martin McKee, Professor of European Public
Health, London School of Hygiene and Tropical Medicine,
London, UK
Email:  martin.mckee{at}lshtm.ac.uk
 

(3)  STUDY RAISES CONCERNS OVER PUBLICATION
OF UNETHICAL RESEARCH

(Failure to report ethical approval in child health research:
review of published papers)
http://bmj.com/cgi/content/full/323/7308/318

Forty per cent of research papers published in five American
medical journals failed to report ethical approval or informed
consent, despite the fact that all journals explicitly ask authors
to document approval, finds a study in this week's BMJ. This
raises concerns about the protection of human participants in
clinical trials.

All research reports relating to child health published in 1999
in five American medical journals were reviewed for any
statement about informed consent or ethics committee
approval. All five journals require studies with human
participants to report ethical approval. Of 561 studies, 40%
did not report ethical approval.

Investigators may have failed to obtain and report ethical
approval because of confusion about the requirements,
suggest the authors. Alternatively, some researchers may have
deliberately disregarded ethical approval standards and laws.
Such occurrences are likely to be rare, but they are not
inconceivable, they add.

Protecting participants in clinical research is, and must remain,
one of the highest priorities of medicine, say the authors. They
recommend that medical journals can play a greater role in
protecting human participants by ensuring that every research
study includes a statement regarding human subjects and any
reasons for exemption are provided.

Contact:

Howard Bauchner, Child and Adolescent Health Scholar,
Agency for Healthcare Research and Quality, Rockville, MD,
USA
Email:  howard.bauchner{at}bmc.org
 

(4)  SINGLEHANDED DOCTORS ARE NOT
UNDERPERFORMING

(Do single handed practices offer poorer care?: cross
sectional survey of processes and outcomes)
http://bmj.com/cgi/content/full/323/7308/320

Singlehanded general practitioners in the United Kingdom are
not underperforming clinically, despite government concerns
about professional isolation and quality standards, finds a
study in this week's BMJ.

Researchers compared the performance of 206 singlehanded
practices and 606 group practices in the Trent region of the
United Kingdom using information on hospital admissions and
achievement of clinical targets within the practice. The team
found important differences for three types of hospital
admission. However, after taking other practice characteristics
into account - such as level of deprivation, the percentage of
black and Asian residents and the proportion of patients over
75 years - there were no remaining substantial differences.

We have found no evidence in this study that singlehanded
general practitioners are underperforming clinically, say the
authors. Despite some important limitations, the results offer
insight into the structural differences between the two types of
practice and underline the importance of other practice
characteristics such as deprivation, they conclude.

Contact:

Julia Hippisley-Cox, Senior Lecturer in General Practice,
Nottingham University, Nottingham, UK
Email:  julia.hippisley-cox{at}nottingham.ac.uk


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