Releases Saturday 8 September 2001
No 7312 Volume 323

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(1) MENINGITIS IN INFANCY LINKED TO
DEVELOPMENTAL PROBLEMS

(2) HEARING LOSS IN CHILDREN IS HIGHER
THAN PREVIOUSLY THOUGHT

(3) WHY DO MORE MEN DIE FROM HEART
DISEASE THAN WOMEN?

(4) FLAWS IN NEW ELDERLY CARE
REGULATIONS MAY PUT PATIENTS AT RISK



(1) MENINGITIS IN INFANCY LINKED TO
DEVELOPMENTAL PROBLEMS

(Meningitis in infancy in England and Wales: follow up
at age 5 years)
http://bmj.com/cgi/content/full/323/7312/533

(Editorial: Legacy of bacterial meningitis in infancy)
http://bmj.com/cgi/content/full/323/7312/523

Children who get meningitis in their first year of life have
a 10-fold increased risk of severe or moderate disability
at 5 years of age compared with other children,
concludes a study in this week's BMJ. These findings
provide a complete picture of the range of problems
experienced by children from England and Wales who
have had meningitis in infancy.

Over 1,700 children who survived an acute attack of
meningitis between 1985 and 1987 were identified.
Children of the same age and sex, but who hadn't had
meningitis, served as a control group. General
practitioners and parents of children in both groups
completed a questionnaire about the children's health
and development. Children were allocated to one of
four categories of disability, based on evidence of
developmental problems.

Two per cent of children who survived the acute attack
died before the age of 5 years. Among the survivors
there was a 10-fold increase in the risk of severe or
moderate disability compared with the control group.
They also had an increased risk of mild disorders such
as middle ear disease, squint, and behavioural
problems. The researchers also found that children who
had meningitis as newborns had more health and
development problems than those infected after one
month of age. The rates of disability also varied widely
in children infected with different strains of bacteria.

In an accompanying editorial, Professor Keith
Grimwood believes that doctors need not only to check
vision and hearing after bacterial meningitis but also to
ensure that caregivers and schoolteachers are aware of
possible language deficits and problems understanding
language based material. "Simple educational
interventions may help compensate for these deficits,
improving academic performance, behaviour and self
esteem," he concludes.

Contacts:

Helen Bedford, Senior Research Fellow, Institute of
Child Health, London, UK
Email: h.bedford@ich.ucl.ac.uk

John de Louvois, Director, Public Health Laboratory
Service, Environmental Surveillance Unit, London, UK

David Harvey, Professor of Paediatrics and Neonatal
Medicine, Queen Charlotte's and Chelsea Hospital,
London, UK

(2) HEARING LOSS IN CHILDREN IS HIGHER
THAN PREVIOUSLY THOUGHT

(Prevalence of permanent childhood hearing impairment
in the United Kingdom and implications for universal
neonatal hearing screening: questionnaire based
ascertainment study)
http://bmj.com/cgi/content/full/323/7312/536

(Commentary: Universal newborn hearing screening:
implications for coordinating and developing services
for deaf and hearing impaired children)
http://bmj.com/cgi/content/full/323/7312/536

(Editorial: Measuring the prevalence of permanent
childhood hearing impairment)
http://bmj.com/cgi/content/full/323/7312/525

Far more children in the United Kingdom suffer with
permanent hearing impairment by the age of 9 years
than previously estimated, find researchers in this
week's BMJ. This has important implications for
co-ordinating services for deaf and hearing impaired
children.

Postal questionnaires were used to identify over 17,000
children throughout the UK with permanent hearing
impairment. The level of hearing impairment increased
until the age of 9 years to a significantly higher plateau
than previous studies have estimated. The team
calculated that for every 10 children with a permanent
hearing impairment detected, another five to nine
children (50-90%) would develop a hearing impairment
by the age of 9 years.

These additional children would include some with
inherited impairments who either miss hearing screening
as newborns or pass the screening despite having a
hearing impairment, some who acquire an impairment
(for example, after meningitis) and others who develop
late onset or progressive impairments, explain the
authors.

Unless newborn screening programmes in the UK
improve, significant numbers of children will still need to
be diagnosed with each passing year, warn the authors.
Child audiology services must have the capacity to
achieve early identification and confirmation of these
additional cases, they conclude.

Contacts:

Adrian Davis, Epidemiologist, MRC Institute of Hearing
Research, Nottingham, UK
Email: Adrian@ihr.mrc.ac.uk

Shirley Russ, Assistant Professor of Pediatrics,
Department of Primary Care Pediatrics, Cedars-Sinai
Medical Center, Los Angeles, USA
Email: shirlyruss@aol.com

(3) WHY DO MORE MEN DIE FROM HEART
DISEASE THAN WOMEN?

(Sex matters: secular and geographical trends in sex
differences in coronary heart disease mortality)
http://bmj.com/cgi/content/full/323/7312/541

In most industrialised countries more men die from
coronary heart disease than women but what causes
these sex differences?

The most widely accepted explanation is that the
hormone oestrogen protects women, yet a study in this
week's BMJ suggests that sex differences are largely
the result of environmental factors. If so, it may be
possible to reduce deaths in men to levels similar to
those found in women.

Using several national and international data sources,
researchers at Bristol University examined trends in
deaths from coronary heart disease in men and women
from different countries. From 1949, in England and
Wales, these trends show a marked increase of deaths
among men, peaking in the early 1970s. Rates in
women over the same period were stable or declined.
Similar trends were seen in Australia, France, Sweden,
and the United States.

A protective effect of oestrogen alone cannot explain
these trends because it is inconceivable that levels of
oestrogen in women have changed dramatically over the
past century or vary greatly among women of different
countries, say the authors. Instead, they are largely the
result of environmental factors that affect only men.

Understanding more about the factors that cause the
sex differences in deaths from coronary heart disease
has important public health implications, particularly in
countries or parts of countries where death rates for
coronary heart disease are currently increasing, they
conclude.

Contact:

Debbie Lawlor, Lecturer in Epidemiology and Public
Health Medicine, Department of Social Medicine,
University of Bristol, UK
Email: D.A.Lawlor@bristol.ac.uk

(4) FLAWS IN NEW ELDERLY CARE
REGULATIONS MAY PUT PATIENTS AT RISK

(Caring for older people in the private sector in
England)
http://bmj.com/cgi/content/full/323/7312/566

The regulatory system that is supposed to protect
private nursing home residents in England and Wales is
flawed because of compromises made by the
government, suggest researchers at University College
London in this week's BMJ.

As over half of the healthcare beds in the United
Kingdom are in independent nursing homes for older
people, adequate staffing, monitoring, enforcement, and
accountability are key to delivering good quality care,
they write.

Under new legislation, which comes into force in
England and Scotland in 2002, responsibility for
registering and inspecting homes and enforcing
regulations will be transferred to the National Care
Standards Commission in England, the National
Assembly for Wales, and the Scottish Commission for
the Regulation of Care. Yet, since the mid-1980s the
number of places in nursing homes in England has
increased sevenfold but the number of inspectors has
only tripled. Furthermore, little attention has been paid
to what structures and mechanisms will be required to
ensure high quality care and accountability to users.

In particular the government has failed to stipulate
national minimum standards in the key area of staffing
against all the international evidence.

A Treasury commissioned report recently highlighted
the difficulty for accounting for public funds when care
is provided by the private sector and the need for
government to put in place robust mechanisms to
safeguard all clients and those on behalf of whom it is
commissioning services. The paper highlights the
absence of information on and monitoring of the
healthcare needs of some 500,000 vulnerable residents
in care homes.

International evidence shows that public information on
quality of care, staffing and good systems for public
accountability are essential to help prevent the risk of
regulators and government being pressurised, captured
and paralysed by the private sector industry.

If new regulations are to protect patients, they must be
strengthened to ensure that frail and vulnerable elderly
people are not at increased risk of neglect and poor
quality care, they conclude.

Contact:

Allyson Pollock, Professor, School of Public Policy,
University College London, UK
Email: allyson.pollock@ucl.ac.uk


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