Releases Saturday 16 March 2002
No 7338 Volume 324

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(1)  ACTION TO PREVENT DIABETES SHOULD BEGIN IN
CHILDHOOD

(2)  PATIENT LEAFLETS MAY NOT BE EFFECTIVE IN
THE REAL WORLD

(3)  DEMAND FOR EMERGENCY AMBULANCES HAS
RISEN

(4)  GUIDELINES NEEDED TO PREVENT SPREAD OF
INFECTION IN EUROPEAN HOSPITALS

(5)  STRINGENT REGULATION OF TRADITIONAL
MEDICINES IS URGENTLY NEEDED


 

(1)  ACTION TO PREVENT DIABETES SHOULD BEGIN IN
CHILDHOOD

(Early evidence of ethnic differences in cardiovascular risk:
cross sectional comparison of British South Asian and white
children)
http://bmj.com/cgi/content/full/324/7338/635

(Editorial: Epidemic of cardiovascular disease in South
Asians)
http://bmj.com/cgi/content/full/324/7338/625

Action to prevent non-insulin dependent diabetes and heart
disease in South Asian people may need to begin during
childhood, finds a study in this week's BMJ.

Researchers in London identified 3,415 white and 227 South
Asian children aged 8 to 11 years from primary schools in 10
British towns. Blood samples were taken from 1,287 white
and 73 South Asian children.

An early stage in the development of diabetes and heart
disease risk is insulin resistance, when insulin levels are
increased. The researchers found that South Asian children
showed higher average levels of insulin and insulin resistance
than white children. These ethnic differences were not
associated with corresponding differences in adiposity
(fatness), say the authors.

Insulin metabolism seems to be more sensitive to a given
degree of adiposity among the South Asian children compared
with white children, add the authors. They suggest that the
prevention of insulin resistance and its consequences may
need to begin during childhood.

Contact:

Peter Whincup, Professor of Cardiovascular Epidemiology, St
George's Hospital Medical School, London, UK
Email: p.whincup{at}sghms.ac.uk
 

(2)  PATIENT LEAFLETS MAY NOT BE EFFECTIVE IN
THE REAL WORLD

(Use of evidence based leaflets to promote informed choice
in maternity care: randomised controlled trial in everyday
practice)
http://bmj.com/cgi/content/full/324/7338/643

(Qualitative study of evidence based leaflets in maternity
care)
http://bmj.com/cgi/content/full/324/7338/639

Leaflets used to promote informed choice in women using
maternity services in the UK are not effective in everyday
practice, say researchers from Sheffield University in this
week's BMJ.

Thirteen maternity units in Wales participated in the study.
Units either used leaflets to promote informed choice
(intervention units) or continued with usual care (control
units).

Questionnaires were then sent to four different samples of
women using these maternity services. Women in the
antenatal samples received the questionnaire 28 weeks into
their pregnancy, and women in the postnatal samples received
the questionnaire eight weeks after delivering their babies.

There was no change in the proportion of women who
reported exercising informed choice in the intervention units
compared with the control units for either antenatal or
postnatal women. Only 70% of women in the intervention
units reported being given at least one of the leaflets,
indicating problems with implementation.

The leaflets did not help to promote informed choice in
maternity care, say the authors. They suggest that decision
aids may not be effective in the real world.

Within the same study, Helen Stapleton and colleagues found
that time constraints and other pressures on health
professionals resulted in a lack of discussion of the content of
the leaflets. Health professionals also promoted normative
practices rather than choice and, as women valued their
opinions, this ensured informed compliance rather than
informed choice.

They conclude that these leaflets are unlikely to promote
informed choice in maternity care unless they are introduced
as part of a coherent strategy addressing power imbalances
and the ambiguities currently underpinning choice.

Contacts:

Alicia O'Cathain, Research Fellow, School of Health and
Related Research, University of Sheffield, Sheffield, UK
Email: a.ocathain{at}sheffield.ac.uk

Helen Stapleton, Research Midwife, School of Nursing and
Midwifery, University of Sheffield, Sheffield, UK
Email: h.stapleton{at}sheffield.ac.uk
 

(3)  DEMAND FOR EMERGENCY AMBULANCES HAS
RISEN

(Trends in demand for emergency ambulance services in
Wiltshire over nine years: observational study)
http://bmj.com/cgi/content/full/324/7338/646

Demand for emergency ambulances in the United Kingdom is
rising. A study in this week's BMJ examines the reasons for
this rise.

Researchers analysed emergency ambulance dispatches
using a randon sample of records held by Wiltshire
Ambulance Service NHS Trust. They identified details of
6,100 calls relating to 5,821 incidents over a nine year period.

The proportion of incidents in response to a call from a
general practitioner, or incidents where one was present,
remained fairly constant over the study period, whereas the
proportion of calls made by patients and relatives rose from
12% to 20%.

The category "sudden illness at home" showed an increase
out of line with that seen overall. Incidents described as
"collapse" fell from 35% to 20%, whereas those attributed
more specifically to cardiac problems rose from 22% to 31%
and those attributed to respiratory problems from 12% to
21%. This suggests that people are using more specific
terminology to describe emergency incidents, say the authors.

Demand for emergency ambulances has risen, say the
authors. Although this increase is often attributed to general
practitioners redirecting patients with urgent problems to the
ambulance service, particularly out of surgery hours, they
found no evidence of this.

"Research identifying influences on callers' perceptions of
urgency is necessary if we are to improve our understanding
of the demand for emergency care and our ability to plan for
the future," they conclude.

Contact:

Steve George, Reader in Public Health, School of Medicine,
University of Southampton, Southampton, UK
Email: pluto{at}soton.ac.uk
 

(4)  GUIDELINES NEEDED TO PREVENT SPREAD OF
INFECTION IN EUROPEAN HOSPITALS

(What action should be taken to prevent the spread of
vancomycin resistant enterococci in European hospitals?)
http://bmj.com/cgi/content/full/324/7338/666

National and European guidelines to control the spread of
vancomycin resistant enterococci should be drawn up before
these bacteria become endemic in European hospitals, argue
researchers in this week's BMJ.

Vancomycin resistant bacteria have a low virulence but can
cause serious infections in transplant patients or those in
intensive care units. Infections are becoming increasingly
common in American hospitals, but are rare in European
hospitals.

A recent outbreak in a Dutch hospital was halted by strict
infection control measures, but these measures were
expensive and at times stopped new admissions and routine
surgery.

With the American experience in mind, many doctors agree
that spread of these multiple resistant bacteria should be
prevented. On the other hand, a rigorous infection and control
policy will result in extensive patient discomfort, increased
workload for healthcare workers, and substantial extra costs
for healthcare organisations.

The authors propose that a European consensus on control
measures should be reached and guidelines drawn up on how
to approach hospital outbreaks before these bacteria become
endemic in Europe's hospitals.

Contact:

Marc Bonten, Internist, Department of Internal Medicine,
Eijkman-Winkler Institute for Microbiology, Infectious
Diseases, and Inflammation, Netherlands
Email: m.j.m.bonten{at}azu.nl
 

(5)  STRINGENT REGULATION OF TRADITIONAL
MEDICINES IS URGENTLY NEEDED

(Letter: Chinese medicines for slimming still cause health
problems)
http://bmj.com/cgi/content/full/324/7338/679

Traditional Chinese medicines for slimming still cause health
problems and stringent regulation is urgently needed,
according to a letter in this week's BMJ.

Researchers at Southend Hospital in Essex analysed several
slimming preparations and the urine of several patients who
had been attending a particular Chinese herbalist for weight
loss remedies.

They found a high concentration of fenfluramine in tablets
supplied to patients and also in the patients' urine.

After reports of an association with pulmonary hypertension,
fenfluramine was withdrawn even as a prescription only
medicine in 1997. Its use as described is obviously illegal, say
the authors. This case is now under investigation by the
Medicines Control Agency, which has yet to establish exactly
where in the chain of supply adulteration with fenfluramine
occurred.

"The vast majority of Chinese herbalists and practitioners of
other traditional medicines are responsible, professional, and
caring," say the authors. "Our recent experience, however,
highlights how the public's trend to believe, often with great
naivety, in natural remedies can be abused. Stringent
regulation of traditional medicines, at least to the standards of
conventional practice, is urgently needed."

Contact:

Cathryn Corns, Consultant Biochemist, Southend Hospital,
Westcliff-on-Sea, Essex, UK
 


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