Releases Saturday 27 April 2002
No 7344 Volume 324

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(1) SIMPLE BREATH TEST MAY REPLACE
ENDOSCOPY

(2) WHAT CAUSES PATIENTS TO DELAY
SEEKING MEDICAL HELP?

(3) HOSPITAL MORTUARY SERVICES NEED
REGULAR INSPECTION

(4) SEX AT BIRTH LINKED TO LATITUDE

(5) STANDARDS OF MEDICAL CARE ON
ADVENTURE HOLIDAYS RAISE
CONCERNS



(1) SIMPLE BREATH TEST MAY REPLACE
ENDOSCOPY

(Randomised trial of endoscopy with testing for
Helicobacter pylori compared with non-invasive H
pylori testing alone in the management of dyspepsia)
http://bmj.com/cgi/content/full/324/7344/999

A simple breath test for detecting H pylori infection
is as effective and safe as endoscopy and is less
uncomfortable and distressing for the patient,
conclude researchers in this week's BMJ.

The study involved 708 patients with indigestion
who had been referred to hospital for endoscopic
investigation (examining the stomach using a
tube-like viewing instrument).

A total of 356 patients received a non-invasive
breath test for H pylori and 352 received
endoscopy plus H pylori testing. Patients were also
asked to score the degree of discomfort or distress
caused by their test, and whether they would have
the same test again.

After 12 months, non-invasive testing for H pylori
was as effective and as safe as endoscopy.
Furthermore, it was as reassuring to the patient as
endoscopy, less uncomfortable and distressing, and
substantially cheaper than endoscopy.

"For these reasons, non-invasive H pylori testing
seems to be the preferred investigation for patients
with uncomplicated dyspepsia," conclude the
authors.

Contact:

K McColl, Professor of Gastroenterology,
University Department of Medicine and
Therapeutics, Western Infirmary, Glasgow,
Scotland
Email: K.E.L.McColl@clinmed.gla.ac.uk

(2) WHAT CAUSES PATIENTS TO DELAY
SEEKING MEDICAL HELP?

(Decision making processes in people with
symptoms of acute myocardial infarction: qualitative
study)
http://bmj.com/cgi/content/full/324/7344/1006

What causes patients with symptoms of a heart
attack to delay seeking medical help?

Researchers in this week's BMJ interviewed 22
patients who had been admitted to hospital with at
least one previous heart attack. Six themes
emerged that seemed to influence their decision to
seek medical help.

Many patients thought that their symptoms were
not severe enough to be a heart attack, confusing
them with symptoms of angina or indigestion. Some
who had already had treatment believed they were
no longer at risk of another heart attack.

Twenty patients reported that the symptoms were
not similar to those of any previous attack, while
others admitted that, illogically, they "hoped it
would go away."

All but one of the patients felt a concern about
wasting NHS time and resources, especially
ambulances. Even those who had previously been
told to phone an ambulance felt reluctant to do so.
People were also reluctant to seek medical help
during the night and at weekends.

The decision to seek medical help is a complex
interaction of knowledge and experience, beliefs,
emotions, and the context of the event, say the
authors. Simply providing patients with information
on symptoms of a heart attack, and what to do in
the event of these symptoms, may not be sufficient
to promote prompt action, they conclude.

Contact:

Jill Pattenden, Research Fellow, Department of
Health Sciences, University of York, UK
Email: jp30@york.ac.uk

(3) HOSPITAL MORTUARY SERVICES NEED
REGULAR INSPECTION

(Prospective audit of records of deceased patients
received in hospital mortuary)
http://bmj.com/cgi/content/full/324/7344/1009

Recent stories about improper storage of bodies
and organs in hospital mortuaries have generated
public interest in both pathology and mortuary
services.

A study in this week's BMJ suggests that regular
audits are essential for a mortuary to run effectively
and safely and to gain public confidence.

Researchers at the Walsall Hospitals NHS Trust
audited the documents accompanying all 7,761
deceased patients in the hospital during
1996-2000. Bodies were received from funeral
directors and ambulance crews as well as hospital
wards.

They checked wrist bands, labels, and identification
papers against the patients' registration details for
any discrepancies. They also checked accuracy of
recording the presence of a pacemaker and
property for each body. Bodies for which there
was one or more discrepancy were classified as
failed cases.

In 1996-7, the failure rate for bodies from all
sources was 10%. This figure fell in the study
period to 3% in 1999-2000.

Although some of the discrepancies were arguably
less important, such as errors in unit number or
address, a substantial proportion could have had
serious consequences, say the authors. These
include misidentification of the body (body received
in the mortuary with the wrong name) or property
and non-identification of the pacemakers.

"The error rate fell during our study, probably
because staff were regularly alerted to errors as
part of the audit," say the authors. "We therefore
believe that such audits are essential to mortuary to
run effectively and safely and to gain public
confidence."

Contact:

Ye Lin Hock, Consultant Histopathologist, Walsall
Hospitals NHS Trust, Walsall, West Midlands, UK
Email: Hocky@wht.walsallh-tr.wmids.nhs.uk

(4) SEX AT BIRTH LINKED TO LATITUDE

(Unexplained differences in sex ratios at birth in
Europe and North America)
http://bmj.com/cgi/content/full/324/7344/1010

In Europe, significantly more boys are born in
southern countries than in northern latitudes,
whereas the reverse is found in North America. Yet
the reasons for this remain a mystery, according to
a study in this week's BMJ.

Using data from the World Health Organisation,
researchers in Malta analysed and compared the
male to female ratio in Europe and North America
over 50 years.

Europe was banded by latitude into Southern
countries, Central Europe, and Nordic countries.
The North American continent was divided by
latitude into Canada, the United States, and
Mexico.

They found that significantly more boys were born
in southern countries, such as Greece, Italy, and
Spain than in central Europe or the Nordic
countries. In contrast, a low male to female ratio
was found in Mexico, a higher ratio in the United
States, and an even higher ratio in Canada.

The authors are unable to explain these findings, but
stress that a temperature related effect cannot
account for the differences.

Contact:

Victor Grech, Consultant, Paediatric Department,
St Luke's Hospital, Guardamangia, Malta
Email: victor.e.grech@magnet.mt

(5) STANDARDS OF MEDICAL CARE ON
ADVENTURE HOLIDAYS RAISE
CONCERNS

(Letter: Tour operators should tell clients about
potential risks of adventure holidays)
http://bmj.com/cgi/content/full/324/7344/1040

Standards of medical care and safety provided by
tour operators on adventure holidays in remote
mountainous regions of the world are called into
question in this week's BMJ.

Fionn Bellis, Specialist Registrar in Accident and
Emergency Medicine, argues that although some
companies provide their own medically trained
staff, they may rely on doctors on holiday with the
group to provide help.

Twice in the past year, she recalls treating fellow
travellers with acute mountain sickness while on
holiday - a common and potentially fatal condition if
not treated correctly. In both cases the group
leaders had exceeded the recommended rates of
ascent, and the people concerned were unaware of
the severity of the risks of travel to high altitude,
says the author.

The public should be properly informed about the
health and safety risks of certain destinations before
departure, writes the author. Currently, neither Air
Travel Organisers' Licensing (ATOL) nor the
Association of British Travel Agents provides
guidance for this. The medical profession should
also take a leading role in persuading travel
companies to give their clients detailed information
of the potential health risks of travel so that they
can make informed decisions about whether to visit
these destinations.

Adherence to standards of best medical and safety
practice to prevent acute mountain sickness and
other conditions should be mandatory for tour
operators, she concludes.

Contact:

Fionn Bellis, Specialist Registrar in Accident and
Emergency Medicine, Torbay Hospital, Torquay,
Devon, UK
Email: fionnbellis@hotmail.com


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