Saturday 22 February 2003
No 7386 Volume 326

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(1)  TOO MUCH COFFEE DURING PREGNANCY
RISKS STILLBIRTH

(2)  HIGHER RISKS FOR WOMEN WITH DIABETES
USING HRT

(3)  LINK FOUND BETWEEN SPONTANEOUS
ABORTION AND HEART DISEASE

(4)  DOCTORS MAY OMIT INFORMATION WHEN
COPYING LETTERS TO PATIENTS



 

(1)  TOO MUCH COFFEE DURING PREGNANCY
RISKS STILLBIRTH

(Maternal consumption of coffee during pregnancy and
stillbirth and infant death in first year of life: prospective
study)
http://bmj.com/cgi/content/full/326/7386/420

Pregnant women who drink eight or more cups of coffee
a day run more than twice the risk of stillbirth compared
with women who do not drink coffee, finds a study in this
week's BMJ.

Researchers in Denmark identified 18,478 pregnant
women booking for delivery at Aarhus University Hospital
during 1989-96. The women completed two
questionnaires, providing information such as medical
history, smoking habits, alcohol and coffee consumption.

The risk of stillbirth increased with the number of cups of
coffee a day during pregnancy. Compared with women
who did not drink any coffee, women who drank four to
seven cups a day had an 80% increased risk of stillbirth,
and women who drank eight or more cups a day a 300%
increased risk. There was no association between coffee
consumption and death in the first year of life.

Women with a high intake of coffee are more likely to be
smokers and to have a high intake of alcohol, say the
authors. Adjusting for these factors reduced the risk
slightly, but the link remained significant.

Contact:

Kirsten Wisborg, Specialist Registrar, Perinatal
Epidemiological Research Unit, Department of Obstetrics
and Gynaecology, Aarhus University Hospital, Denmark
Email: kiwi{at}perinatal.dk
 

(2)  HIGHER RISKS FOR WOMEN WITH DIABETES
USING HRT

(Relation between hormone replacement therapy and
ischaemic heart disease in women: prospective
observational study)
http://bmj.com/cgi/content/full/326/7386/426

Women with diabetes who use hormone replacement
therapy are at an increased risk of death from all causes
and heart disease, finds a study in this week's BMJ.

Using data from a group of Danish nurses, researchers
examined the association between hormone replacement
therapy and ischaemic heart disease, heart attack, and
total number of deaths among 13,084 postmenopausal
women.

They found that hormone replacement therapy did not
protect women against heart disease or heart attack, but
there was a significantly increased risk of death from all
causes and ischaemic heart disease among women with
diabetes.

This effect was not influenced by other risk factors for
heart disease, such as smoking, alcohol consumption, and
body mass index, say the authors.

Reasons for the harmful effect of hormone replacement
therapy among women with diabetes are inconclusive, but
could be explained by an influence on blood sugar control,
they conclude.

Contact:

Ellen Løkkegaard, Research Fellow, Department of
Obstetrics and Gynaecology, Hvidovre University
Hospital, Hvidovre, Denmark
Email: loekkegaard{at}dadlnet.dk
 

(3)  LINK FOUND BETWEEN SPONTANEOUS
ABORTION AND HEART DISEASE

(Spontaneous loss of early pregnancy and risk of
ischaemic heart disease in later life: retrospective cohort
study)
http://bmj.com/cgi/content/full/326/7386/423

For the first time, a specific link has been found between
spontaneous abortion and risk of heart disease in later life,
according to researchers in this week's BMJ.

The team analysed national data on births in Scotland
during 1981-5 and deaths or hospital admissions due to
ischaemic heart disease (IHD) during 1981-99.

They found that women with a history of spontaneous loss
of early pregnancy were at increased risk of IHD. By
contrast, there was no association between therapeutic
abortion and subsequent risk of IHD.

To our knowledge, this is the first study to show a specific
association between spontaneous abortion and maternal
risk of IHD, say the authors.

However, further studies are required to corroborate
these findings and confirm that the association is
independent of smoking and other factors, such as
maternal disease (for example, diabetes and polycystic
ovarian syndrome), they conclude.

Contact:

Professor Gordon Smith, Department of Obstetrics and
Gynaecology, The Rosie Hospital, Cambridge, UK
Email: gcss2{at}cam.ac.uk
 

(4)  DOCTORS MAY OMIT INFORMATION WHEN
COPYING LETTERS TO PATIENTS

(Letter: Copying letters to patients)
http://bmj.com/cgi/content/full/326/7386/449

From April 2004, patients will receive copies of all
correspondence between clinicians working in the NHS as
a matter of course. However, some doctors are worried
about distressing patients by what they write and
consequently tend to omit information, say researchers in
this week's BMJ.

Their study involved 76 new patients who attended two
psychiatry clinics from January to July 2002 and eight
psychiatrists who worked in these clinics during this time.

After the assessment, patients were sent a copy of the
psychiatrist's letter to the general practitioner and asked to
complete a short questionnaire on their evaluation of the
letter. Psychiatrists were asked whether anything of
importance had been omitted from the letter, if so, why
and how the omitted information would be communicated
to general practitioners.

Fifty six of the 76 letters (74%) were sent to the patient in
an unaltered form. In three cases the psychiatrists thought
it inappropriate for the patient to receive a copy of the
letter, citing concerns over patients' distress. In 17 cases,
clinicians made omissions, mainly of parts of the history.

Reasons cited for omission were fear of distressing the
patient (14 instances), concern about people other than the
patient having access to information (four instances), and
protection of information supplied by third parties (two
instances). General practitioners were informed of the
omitted information, either by letter or in person. Most
patients (33 out of 40) wished to continue receiving copies
of correspondence.

Although patients appreciate receiving copies of letters,
some training and reassurance about this practice may be
needed for doctors before implementation, conclude the
authors.

Contact:

Graham Murray, Research Associate, Department of
Psychiatry, University of Cambridge, Addenbrooke's
Hospital, Cambridge, UK
Email: gm285{at}cam.ac.uk
 


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