Releases Saturday 8 March 2003
No 7388 Volume 326

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(1) WOMEN WITH COSMETIC BREAST IMPLANTS
MORE LIKELY TO COMMIT SUICIDE

(2) (TREATING MS IS EXPENSIVE, BUT COST
FALLS OVER TIME

(3) MORE EVIDENCE NEEDED ON TRUE IMPACT
OF NHS WALK-IN CENTRES

(4) EMERGENCY CARE SCHEME DOES NOT
TACKLE REAL PROBLEMS



(1) WOMEN WITH COSMETIC BREAST IMPLANTS
MORE LIKELY TO COMMIT SUICIDE

(Total and cause specific mortality among Swedish
women with cosmetic breast implants: prospective study)
http://bmj.com/cgi/content/full/326/7388/527

Women who undergo cosmetic surgery for breast
augmentation are more likely to commit suicide than
women from the general population, finds a study in this
week's BMJ.

Researchers identified 3,521 Swedish women aged
15-69 years who had had breast implants between 1965
and 1993. They compared the observed number of
deaths with the expected number of deaths from suicide,
unintentional injury, cardiovascular diseases,
malignancies, and other causes over an average of 11
years.

Although 59 deaths were expected, 85 women died.
Fifteen women committed suicide, compared with 5.2
expected deaths from suicide. Excess deaths were also
due to malignant disease, mainly lung cancer due to
smoking. The number of deaths for all other causes was
close to expected.

Given the well documented link between psychiatric
disorders and a desire for cosmetic surgery, the
increased risk for death from suicide may reflect a
greater prevalence of psychopathology rather than a
causal association between implant surgery and suicide,
say the authors.

Surgeons evaluating candidates for breast implant
surgery need to be vigilant for subtle signs of psychiatric
problems, they conclude.

Contact:

Veronica Koot, Clinician and Epidemiologist, Julius
Centre for Health Sciences and Primary Care, University
Medical Centre, Utrecht, Netherlands
Email: kuckkoot@ikmn.nl

(2) (TREATING MS IS EXPENSIVE, BUT COST
FALLS OVER TIME

(Modelling the cost effectiveness of interferon beta and
glatiramer acetate in the management of multiple
sclerosis)
http://bmj.com/cgi/content/full/326/7388/522

The cost of drug treatment multiple sclerosis is high, but
decreases with prolonged treatment up to 20 years,
concludes a study in this week's BMJ.

Researchers evaluated the cost effectiveness of four
drugs currently licensed for the treatment of multiple
sclerosis in the United Kingdom (three interferon betas
and glatiramer acetate). They assessed the effect of each
drug against conventional management over 20 years
using the best available evidence.

They calculated that the cost of each year of life saved or
prolonged by using any of the four treatments ranged
from £42,000 to £98,000. Price had a considerable
effect on the cost effectiveness for each drug.

The authors stress, however, that uncertainty surrounding
these estimates is substantial, largely due to the
unpredictability of the disease and the difficulty in
capturing all aspects of its impact on patients. Further
research to establish the true impact of these treatments
would be of considerable value, they conclude.

In the face of such uncertainties, the Department of
Health has introduced a risk-sharing scheme for
providing these treatments in the NHS, writes Professor
David Miller in an accompanying commentary. Although
the scheme will need substantial investment, it is a
constructive approach in addressing a difficult problem,
and it is hard to see a realistic alternative.

Further research is needed to identify those who will
benefit most from disease modifying treatments.
Meanwhile, work must go on to develop more effective
treatments, he concludes.

Contacts:

Paper: Chris McCabe, Senior Lecturer in Health
Economics, School of Health and Related Research,
University of Sheffield, UK
Email: c.mccabe@sheffield.ac.uk

Commentary: David Miller, Professor of Clinical
Neurology, Institute of Neurology and National Hospital
for Neurology and Neurosurgery, London, UK
Email: d.miller@ion.ucl.ac.uk

(3) MORE EVIDENCE NEEDED ON TRUE IMPACT
OF NHS WALK-IN CENTRES

(Effect of NHS walk-in centre on local primary
healthcare services: before and after observational study)
http://bmj.com/cgi/content/full/326/7388/530

(Impact of NHS walk-in centres on the workload of
other local healthcare providers: time series analysis)

BMJ Volume 326, pp 532-4

Introduction of NHS walk-in centres may not affect the
workload of local general practitioners, but more
evidence is needed to determine their true impact on
other local healthcare services, according to two studies
in this week's BMJ.

In the first study, researchers compared the activity of
primary and emergency healthcare services for two
towns in Leicestershire, before and after a walk-in centre
opened in one of the towns.

They found no significant effect on general practice
emergency consultations, the availability of routine
appointments, use of out of hours services, or the
number of calls to NHS Direct. However, the workload
of the local minor injuries unit increased significantly,
probably because it was in the same building as the
walk-in centre.

In the second study, researchers assessed the impact of
NHS walk-in centres on the workload of 20 accident
and emergency departments, 40 general practices, and
14 out of hours services in England.

They found a reduction in consultations at emergency
departments and general practices close to walk-in
centres, although these reductions were not statistically
significant. Walk-in centres did not have any impact on
out of hours services.

To determine whether walk-in centres reduce the
demand on other local NHS providers will require study
of a large number of sites over a prolonged period, they
conclude.

Contacts:

Paper 1: Ronald Hsu, Clinical Lecturer in Epidemiology
and Public Health, Department of Epidemiology and
Public Health, University of Leicester, UK
Email: rth4@leicester.ac.uk

Paper 2: Melanie Chalder, Senior Research Associate,
Cardiff University School of Social Sciences, Cardiff,
UK
Email: chalderm@cardiff.ac.uk

(4) EMERGENCY CARE SCHEME DOES NOT
TACKLE REAL PROBLEMS

(Letters: Inversion of emergency pyramid)
http://bmj.com/cgi/content/full/326/7388/553

A new scheme designed to reduce waits in emergency
departments is simply massaging the figures to meet
government targets, warn senior doctors in this week's
BMJ.

The "see and treat" concept involves having senior staff
as the first clinical contact rather than a triage and wait
approach. However, there are serious concerns that
diverting senior clinicians from treating ill patients will be
detrimental.

Adrian Fogarty, a consultant in accident and emergency
medicine at the Royal Free Hospital, argues that there
simply aren't yet sufficient numbers of trained emergency
doctors to take on this workload.

Those senior emergency doctors currently in post find
their time occupied with critically ill patients, together
with complex medical and surgical cases. They simply do
not have the time to deal with "minor" cases as they walk
through the door, he says.

The NHS Modernisation Agency needs to realise that
there will not be a quick fix solution to emergency care
access in this country, at least not without substantial and
sustained investment in appropriately trained staff, he
concludes.

In another letter, Bruce Finlayson, a consultant in
accident and emergency medicine at the Norfolk and
Norwich University Hospital, writes: "Such schemes as
see and treat, while laudable in the big picture, are
methods of massaging the figures towards the
government's four hour emergency targets without
adequately addressing the real problems."

Contact:

Adrian Fogarty, Consultant in Accident and Emergency
Medicine, Royal Free Hospital, London, UK
Email: afogarty@btinternet.com


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