Releases Saturday 6 December 2003
No 7427 Volume 327

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(1) NEW REPORT REVEALS LONG STANDING PROBLEMS IN RESEARCH
STRATEGY

(2) NO RATIONALE FOR GIVING PENICILLIN FOR A SORE THROAT

(3) MORE DOUBTS OVER VALUE OF DEFIBRILLATORS

(4) PATIENTS AND DOCTORS LACK KNOWLEDGE ABOUT ADRENALINE
INJECTIONS


(1) NEW REPORT REVEALS LONG STANDING PROBLEMS
IN NHS RESEARCH STRATEGY

(Increasing the impact of health services research)

http://bmj.com/cgi/content/full/327/7427/1339

(Editorial: Health services research)
http://bmj.com/cgi/content/full/327/7427/1301

Health services research is still not making its full contribution to
improvements in patient care, according to a new report from
The Health Foundation and the Nuffield Trust, summarised in
this week's BMJ.

Health services research accounts for 2-3% of the £4530m
spent on health research in the UK each year, but it is unclear
how much of the information generated is translated and used to
inform practical decisions.

Research for the report involved interviews with 35 senior health
service researchers, NHS managers, policy makers, and research
commissioners in the UK.

It shows that, despite many attempts to streamline NHS research
funding, funders, researchers, and the users of research are
uncertain about how best to work together.

It reveals that both managers and researchers are frustrated
about the applicability of some health services research, while
responsibility for communicating the results of research to the
people who need it is also unclear.

The report proposes several ways that research could be
strengthened, including a UK Academy for Health Services
Research, the development of "knowledge translators", and
fellowships that build strategic alliances between the NHS,
academics, and policy makers.

Everyone involved in health services research recognises
the existence of long-standing problems, say the authors.
The best chance of progress lies in bringing together funders,
users, and researchers to develop solutions, as has been
achieved in the United States and Canada.

The Health Foundation is calling for comments on a range
of proposals for action to support a new programme of
activity to help develop health services research. The Nuffield
Trust will also be taking forward a number of initiatives in this area.

Contact:

Gemma Marenghi, Media & Communications Officer, The
Health Foundation, London, UK Email:
gemma.marenghi@health.org.uk

(2) NO RATIONALE FOR GIVING PENICILLIN FOR
A SORE THROAT

(Penicillin for acute sore throat in children: randomised,
double blind trial)

http://bmj.com/cgi/content/full/327/7427/1324

Most children should not be given penicillin for a sore throat,
finds a study in this week's BMJ.

Dutch researchers identified 156 children aged 4-15 who
visited their family doctor with a severe sore throat. The
children were randomly assigned to penicillin for seven
days, penicillin for three days followed by placebo for four
days, or placebo for seven days.

Penicillin did not reduce the duration of symptoms, nor
did it affect school attendance or recurrences of sore throat.

Penicillin may, however, reduce the development of
complications, such as quinsy or scarlet fever. Although,
once a complication is diagnosed, sufficient time is left to
start antibiotic treatment, say the authors.

The authors advocate prudent prescription behaviour with
respect to penicillin. General practitioners should treat
children with an acute sore throat only when they are severely
ill or are at high risk of developing serious complications,
they conclude

Contact:

Sjoerd Zwart, General Practitioner, Julius Center for Health
Sciences and Primary Care, University Medical Center
Utrecht, Netherlands Email: S.Zwart@med.uu.nl

(3) MORE DOUBTS OVER VALUE OF
DEFIBRILLATORS

(Use of automated external defibrillator by first
responders in out of hospital cardiac arrest:
prospective controlled trial)

http://bmj.com/cgi/content/full/327/7427/1312

(Cost effectiveness and cost utility model of public
place defibrillators in improving survival after
prehospital cardiopulmonary arrest)
http://bmj.com/cgi/content/full/327/7427/1316

Use of defibrillators by police and fire fighters to emergency
calls shows only a modest benefit, finds a study in this week's
BMJ. A second study shows that public place defibrillators
are not good value for money.

In the first study, defibrillators were provided to one fire
brigade region and two police districts in and around Amsterdam.
Half of the fire brigade region and police districts served as
the control area. Every four months the experimental and
control areas changed over.

Use of defibrillators did not significantly increase survival to
hospital discharge, although it did improve return of spontaneous
circulation and admission to hospital. The authors suggest that
improved dispatch procedures should increase the success of
the programme.

In the second study, researchers calculated the cost efficiency of
locating defibrillators in all major airports, railway stations, and
bus stations across Scotland.

They concluded that public place defibrillators exceed the
commonly used cut-off levels for funding and represent poorer
value for money than some alternative strategies.

Contacts:

Study 1: Anouk van Alem, Department of Cardiology, Academic
Medical Centre, Amsterdam, Netherlands
Email: a.p.vanalem@amc.uva.nl

Study 2: Jill Pell, Consultant in Public Health Medicine, Greater
Glasgow NHS Board, Scotland or Andrew Walker, Senior
Lecturer in Health Economics, University of Glasgow, Scotland

(4) PATIENTS AND DOCTORS LACK KNOWLEDGE
ABOUT ADRENALINE INJECTIONS

(Knowledge about using auto-injectable adrenaline: review
of patients' case notes and interviews with general
practitioners)

http://bmj.com/cgi/content/full/327/7427/1328

Patients and general practitioners lack knowledge of how and
when to use devices to inject adrenaline after anaphylaxis
(severe allergic reactions), finds a study in this week's BMJ.

Researchers assessed the knowledge of 60 patients (or
their parents) who had been prescribed injectable adrenaline
and 50 general practitioners about their understanding of
when and how injectable adrenaline should be used.

Two of the 14 adults and the parents of only 16 of the 46
children knew when and how to use injectable adrenaline.
Overall, fewer than a third of patients or parents had adequate
knowledge of when and how to use the device.

Only one general practitioner knew how to use the device,
because of a personal history of anaphylaxis.

None of the general practitioners personally showed patients
how or when to use the device, and over half (26) would not
advise patients to go to hospital after taking adrenaline for
anaplylaxis. This is in contrast to recommended practice.

Current provision in the United Kingdom for patients with
allergies is poor, and patients may have to wait between
diagnosis of anaphylaxis and assessment by a specialist, say
the authors. Prescribers should therefore ensure that patients
and parents are properly educated, they conclude.

Contact:

Dr Amolak Bansal, Clinical Immunologist, Epsom and St Helier
NHS Trust, Carshalton, Surrey, UK


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