Stop exploiting orphan drugs
	Fiona Godlee
	BMJ  2010;341:c6587 (Published ) [Extract] [Full text] [Request Permissions]

Editorials

This week's Editorials [PDF]

	The problem of orphan drugs
	Robin E Ferner, Dyfrig A Hughes
	BMJ  2010;341:c6456 (Published ) [Extract] [Full text] [Request Permissions]

	Suicide attempts in people taking isotretinoin for acne
	Parker Magin, John Sullivan
	BMJ  2010;341:c5866 (Published ) [Extract] [Full text] [Request Permissions]

	Doctors and climate change
	Ian Roberts, Robin Stott, On behalf of the Climate and Health Council executive
	BMJ  2010;341:c6357 (Published ) [Extract] [Full text] [Request Permissions]

Letters

This week's Letters [PDF]

	Estimating HIV prevalence: A cautious note on household surveys in poor settings
	Wendy Janssens, Ingrid de Beer, Hannah M Coutinho, Gert van Rooy, Jacques van der Gaag, Tobias F Rinke de Wit
	BMJ  2010;341:c6323 (Published ) [Extract] [Full text] [Request Permissions]

	Data openness: Reporting of absolute risk
	Mark J Bolland, Andrew Grey
	BMJ  2010;341:c6331 (Published ) [Extract] [Full text] [Request Permissions]

	Data openness: Absolute v relative risk reduction
	Paul E Norman
	BMJ  2010;341:c6333 (Published ) [Extract] [Full text] [Request Permissions]

	Data openness: Independent public inquiries needed to ensure drug safety
	Brian Edwards
	BMJ  2010;341:c6336 (Published ) [Extract] [Full text] [Request Permissions]

	Reboxetine in depression: All the relevant data?
	Erick H Turner
	BMJ  2010;341:c6487 (Published ) [Extract] [Full text] [Request Permissions]

	Reboxetine in depression: NICE guidance differs, so where next?
	Rajeev Krishnadas
	BMJ  2010;341:c6484 (Published ) [Extract] [Full text] [Request Permissions]

	Alzheimer's disease/syndrome?: There are two types of disease
	Edo Richard, Willem A Van Gool
	BMJ  2010;341:c6327 (Published ) [Extract] [Full text] [Request Permissions]

	Errors in prescribing: Reducing insulin errors
	Steven J McNulty, Andrew Lewis, Kevin J Hardy
	BMJ  2010;341:c6503 (Published ) [Extract] [Full text] [Request Permissions]

	Errors in prescribing: Spell and write out numbers
	Mona Arora, Amit Arora
	BMJ  2010;341:c6502 (Published ) [Extract] [Full text] [Request Permissions]

	Errors in prescribing: Hypervigilance is needed
	Rowan Mclachlan
	BMJ  2010;341:c6504 (Published ) [Extract] [Full text] [Request Permissions]

	Request for breast reduction: Don’t forget chronic scar pain
	T Vemmer
	BMJ  2010;341:c6510 (Published ) [Extract] [Full text] [Request Permissions]

	Diabetes: Not every child with diabetes needs insulin
	Dario Iafusco, Andrea E Scaramuzza, Alfonso Galderisi, Alessandra Cocca, Roberto Giugliano, Gian Vincenzo Zuccotti, Francesco Prisco
	BMJ  2010;341:c6512 (Published ) [Extract] [Full text] [Request Permissions]

	Heeding lessons from Shipman: Attention has been distracted
	Alastair M Santhouse
	BMJ  2010;341:c6506 (Published ) [Extract] [Full text] [Request Permissions]

	Heeding lessons from Shipman: Premise is wrongheaded
	Roger A Fisken
	BMJ  2010;341:c6507 (Published ) [Extract] [Full text] [Request Permissions]

News

This week's News [PDF]

	Stroke patients take part in "milestone" UK trial of stem cell therapy
	Jacqui Wise
	BMJ  2010;341:c6574 (Published ) [Extract] [Full text] [Request Permissions]

	Gaps in information are impeding progress in cancer care in England
	Susan Mayor
	BMJ  2010;341:c6590 (Published ) [Extract] [Full text] [Request Permissions]

	In brief
	BMJ  2010;341:c6474 (Published ) [Extract] [Full text] [Request Permissions]

	Community care networks could help 200 000 more people die at home instead of hospital
	Zosia Kmietowicz
	BMJ  2010;341:c6508 (Published ) [Extract] [Full text] [Request Permissions]

	GMC is tougher on child protection doctors than on those who access child porn, conference hears
	Clare Dyer
	BMJ  2010;341:c6562 (Published ) [Extract] [Full text] [Request Permissions]

	Surgeons call for identity of knife crime victims to be shared with police
	Andrew Cole
	BMJ  2010;341:c6579 (Published ) [Extract] [Full text] [Request Permissions]

	Surgeon threatened with libel over remarks made about a breast enhancement cream
	Clare Dyer
	BMJ  2010;341:c6452 (Published ) [Extract] [Full text] [Request Permissions]

	Number of deaths from cholera in Haiti nears 1000
	John Zarocostas
	BMJ  2010;341:c6569 (Published ) [Extract] [Full text] [Request Permissions]

	GSK lawyer is indicted on charges of obstructing FDA proceeding
	Janice Hopkins Tanne
	BMJ  2010;341:c6570 (Published ) [Extract] [Full text] [Request Permissions]

	FDA breached integrity over investigation of contaminated heparin
	Janice Hopkins Tanne
	BMJ  2010;341:c6529 (Published ) [Extract] [Full text] [Request Permissions]

	Drug firm’s legal action against government advisers is described as "intimidation"
	Ray Moynihan
	BMJ  2010;341:c6527 (Published ) [Extract] [Full text] [Request Permissions]

	Fighting big tobacco in Spain
	Aser Garcia Rada
	BMJ  2010;341:c6462 (Published ) [Extract] [Full text] [Request Permissions]

	Family planning loses out to HIV and AIDS in development aid, shows analysis
	Zosia Kmietowicz
	BMJ  2010;341:c6460 (Published ) [Extract] [Full text] [Request Permissions]

	EU drug monitoring agency voices concerns over "legal highs"
	Rory Watson
	BMJ  2010;341:c6491 (Published ) [Extract] [Full text] [Request Permissions]

	Gruesome by design
	Janice Hopkins Tanne
	BMJ  2010;341:c6480 (Published ) [Extract] [Full text] [Request Permissions]

Short Cuts

This week's Short Cuts [PDF]

	All you need to read in the other general journals
	BMJ  2010;341:c6530 (Published ) [Extract] [Full text] [Request Permissions]

Feature

This week's Feature [PDF]

	Drug Regulation: What makes an orphan drug?
	Nigel Hawkes, Deborah Cohen
	BMJ  2010;341:c6459 (Published ) [Extract] [Full text] [Request Permissions]

Observations

This week's Observations [PDF]

	Orphan Drugs: Open letter to prime minister David Cameron and health secretary Andrew Lansley
	David J Nicholl, David Hilton-Jones, Jacqueline Palace,, Sam Richmond, Sarah Finlayson, John Winer, Andrew Weir, Paul Maddison, Nick Fletcher, Jon Sussman, Nick Silver, John Nixon, Dimitri Kullmann, Nick Embleton, David Beeson, Maria Elena Farrugia, Marguerite Hill, Chris McDermott, Gareth Llewelyn, James Leonard, Michael Morris
	BMJ  2010;341:c6466 (Published ) [Extract] [Full text] [Request Permissions]

	Yankee Doodling: Screening for early detection of lung cancer
	Douglas Kamerow
	BMJ  2010;341:c6544 (Published ) [Extract] [Full text] [Request Permissions]

	Medicine and the Media: Private insurers coming to a television screen near you
	Margaret McCartney
	BMJ  2010;341:c6572 (Published ) [Extract] [Full text] [Request Permissions]

Head to Head

This week's Head to Head [PDF]

	Is open peer review the fairest system? Yes
	Trish Groves
	BMJ  2010;341:c6424 (Published ) [Extract] [Full text] [Request Permissions]

	Is open peer review the fairest system? No
	Karim Khan
	BMJ  2010;341:c6425 (Published ) [Extract] [Full text] [Request Permissions]

Analysis

This week's Analysis [PDF]

	Orphan drug pricing may warrant a competition law investigation
	Jonathan C P Roos, Hanna I Hyry, Timothy M Cox
	BMJ  2010;341:c6471 (Published ) [Extract] [Full text] [Request Permissions]

Research

This week's Research [PDF]

	Effect on peer review of telling reviewers that their signed reviews might be posted on the web: randomised controlled trial
	Susan van Rooyen, Tony Delamothe, Stephen J W Evans
	BMJ  2010;341:c5729 (Published ) [Abstract] [Full text] [PDF] [Request Permissions] FREE

	Long term risk for hypertension, renal impairment, and cardiovascular disease after gastroenteritis from drinking water contaminated with Escherichia coli O157:H7: a prospective cohort study
	William F Clark, Jessica M Sontrop, Jennifer J Macnab, Marina Salvadori, Louise Moist, Rita Suri, Amit X Garg
	BMJ  2010;341:c6020 (Published ) [Abstract] [Full text] [PDF] [Request Permissions] FREE

	Association of suicide attempts with acne and treatment with isotretinoin: retrospective Swedish cohort study
	Anders Sundstrom, Lars Alfredsson, Gunilla Sjolin-Forsberg, Barbro Gerden, Ulf Bergman, Jussi Jokinen
	BMJ  2010;341:c5812 (Published ) [Abstract] [Full text] [PDF] [Request Permissions] FREE

	Adoption, non-adoption, and abandonment of a personal electronic health record: case study of HealthSpace
	Trisha Greenhalgh, Susan Hinder, Katja Stramer, Tanja Bratan, Jill Russell
	BMJ  2010;341:c5814 (Published ) [Abstract] [Full text] [PDF] [Request Permissions] FREE

Clinical Review

This week's Clinical Review [PDF]

	Management of venous ulcer disease
	Wijnand Bert van Gent, Esther Dorine Wilschut, Cees Wittens
	BMJ  2010;341:c6045 (Published ) [Extract] [Full text] [Request Permissions]

Practice

This week's Practice [PDF]

	The Competent Novice: Organ donation
	Paul J Frost, Stephen Leadbeatter, Matthew P Wise
	BMJ  2010;341:c6009 (Published ) [Extract] [Full text] [Request Permissions]

	A Patient's Journey: Duchenne muscular dystrophy
	Stefan Spies, Karen Schipper, Frans Nollet, Tineke A Abma
	BMJ  2010;341:c4364 (Published ) [Extract] [Full text] [Request Permissions]

Obituaries

This week's Obituaries [PDF]

	Roger Brearley
	Stephen Brearley
	BMJ  2010;341:c6522 (Published ) [Extract] [Full text] [Request Permissions]

	Anand Dalal
	Leon Poller
	BMJ  2010;341:c6521 (Published ) [Extract] [Full text] [Request Permissions]

	Alan Johnstone
	Nick Johnstone
	BMJ  2010;341:c6523 (Published ) [Extract] [Full text] [Request Permissions]

	Arthur Hugh Lister
	Ian Tring, Don Jones
	BMJ  2010;341:c6526 (Published ) [Extract] [Full text] [Request Permissions]

	Ann Lloyd-Jones (née Parry-Williams)
	Ann Lloyd-Jones, Ruth Stone
	BMJ  2010;341:c6525 (Published ) [Extract] [Full text] [Request Permissions]

	John Fisher Stokes
	Tony Hall, Brian Harrison
	BMJ  2010;341:c6524 (Published ) [Extract] [Full text] [Request Permissions]

Views & Reviews

This week's Views & Reviews [PDF]

	Personal View: Vary VAT on alcohol: a more palatable way to achieve minimum pricing?
	Nick Sheron
	BMJ  2010;341:c6573 (Published ) [Extract] [Full text] [Request Permissions]

	Review of the Week: Die like an Egyptian
	Wendy Moore
	BMJ  2010;341:c6478 (Published ) [Extract] [Full text] [Request Permissions]

	Between the Lines: Who are the sane?
	Theodore Dalrymple
	BMJ  2010;341:c6551 (Published ) [Extract] [Full text] [Request Permissions]

	Medical Classics: Purple America
	Lloyd Bradley
	BMJ  2010;341:c6476 (Published ) [Extract] [Full text] [Request Permissions]

	From the Frontline: Bad medicine: paediatric ear, nose, and throat surgery
	Des Spence
	BMJ  2010;341:c6560 (Published ) [Extract] [Full text] [Request Permissions]

	The Best Medicine: Torture: the bright side
	Liam Farrell
	BMJ  2010;341:c6473 (Published ) [Extract] [Full text] [Request Permissions]

Endgames

This week's Endgames [PDF]

	Picture Quiz: Doc, my knees give way!
	LH Lee, I Gill
	BMJ  2010;341:c5924 (Published ) [Extract] [Full text] [Request Permissions]

	Statistical Question: Skewed distributions II
	Philip Sedgwick
	BMJ  2010;341:c6448 (Published ) [Extract] [Full text] [Request Permissions]

	onExamination Quiz: Thyroid dysfunction
	BMJ  2010;341:c6514 (Published ) [Extract] [Full text] [Request Permissions]

Minerva

This week's Minerva [PDF]

	Rashmi S Manjunatha, Susan Huddart, Varadarajan Baskar
	BMJ  2010;341:c6455 (Published ) [Extract] [Full text] [Request Permissions]

	BMJ  2010;341:c6458 (Published ) [Extract] [Full text] [Request Permissions]

Filler

This week's Filler

	Horse sense
	Anthony Papagiannis
	BMJ  2010;341:c2590 (Published ) [Extract] [Full text] [Request Permissions]

Career focus

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