US Highlights

Here are items from recent BMJ issues that may be of particular interest to American readers. Happy reading. Comments welcome.

Douglas Kamerow
US editor

US editor�s choice

January 28

Andrew Blann and Gregory Lip review the diagnosis and treatment of venous thromboembolism. Their article includes a helpful diagnostic algorithm that facilitates calculating the likelihood of a DVT and emphasizes non-invasive testing. It makes a nice companion piece to the pulmonary embolism review in the January 21st issue.

In the setting of an upcoming Parliamentary debate on banning smoking in British workplaces, American researcher Nadine Leavell and colleagues comment on recent actions by the British American Tobacco Company to promote the effectiveness of air filtration systems. Research says such systems do not protect nonsmokers from adverse health consequences of tobacco smoke, but that doesn�t stop BAT from advocating for them.

In a Personal View, Hasan Tahir and Zafar Iqbal ask whether well-meaning but poorly prepared and disorganized doctors are helping or hurting victims of natural disasters in Sri Lanka and Pakistan. They appeal for better training and more affiliation with ongoing programs that can provide both acute care and necessary follow-up

An anonymous London prostitute reacts to recent UK proposals to decriminalize prostitutes� work while maintaining laws against men who pay for sex. She argues that accepting money for sex is not inherently degrading and does not inevitably lead to coercion, illegal drug use, and child abuse.


January 21

Demosthenes Bouros and colleagues discuss in an editorial whether to use fibrolytics in the treatment of infection-related pleural effusions. Conventional wisdom that installation of fibrolytics helps speed recovery has been tempered by a recent randomized trial that found no benefit from the use of intrapleural streptokinase. The authors point out the weaknesses of that study but still urge caution in the use of these agents.

In a very useful review of the treatment of rheumatoid arthritis, Paul Emery states that a revolution in RA treatment is occurring, one that may lead to thoughts of cure. Treatment with biologic agents that block tumor necrosis factor a is now being used with promising results in relatively early-stage disease and needs to be considered in the care of all newly diagnosed RA patients.

The diagnosis and management of pulmonary embolism is reviewed by Grace Robinson. She emphasizes the importance of pre-test probability in making an often difficult diagnosis. Studies have now shown that subcutaneous low molecular weight heparin is as effective as intravenous heparin in the acute setting, is more convenient, and it may be safer.

 

January 14

In a useful editorial, Mark Schiffman and Phillip Castle discuss the promise of human papilloma virus testing in screening, detection, and monitoring of cervical cancer. Like all screening tests, it has strengths and weaknesses, but their overall conclusion is cautious optimism.

Rachel Huxley and colleagues performed a  meta-analysis of the risk of fatal coronary heart disease in patients with diabetes. They find that diabetes poses a 50% greater risk of death in women than men, which may be due partly to differential effects of the disease but also to less aggressive heart disease treatment of women.

The diagnosis and management of gastro-esophageal reflux disease, called GERD in the US but GORD in the UK, is reviewed by Mark Fox and Ian Forgacs. With the advent of safe and effective proton pump inhibitors, the authors advocate a month�s drug treatment before endoscopy or other diagnostic interventions are ordered.


January 7

BMJ�s first issue of 2006 opens appropriately with a baby story: a case-control study from California that finds that babies using pacifiers (called �dummies� in the UK) were at significantly less risk for sudden infant death syndrome than those who did not. Use of a pacifier seemed to mitigate other SIDS risk factors, such as sleeping in a prone position, use of soft bedding, and having a mother who smoked.

Practical tips from this issue include a reminder from Gerald Liew and colleagues that fundoscopy is twice as accurate when the patient�s pupils are dilated, and that the commonly cited risk of precipitating acute angle closure glaucoma is actually extremely small. Also, Leonard Finegold and Bruce Flamm summarize the evidence for the (increasingly popular) use of magnets to treat pain in various joints: poor.

Peter Goadsby summarizes recent advances in the diagnosis and treatment of migraine headache, the most common disabling headache. We now know that migraine is a brain disorder involving abnormal sensory processing. It can usually be managed well with a combination of acute and preventive treatment.


January 28

Venous thromboembolism
Andrew D Blann, Gregory Y H Lip

Blowing smoke: British American Tobacco's air filtration scheme
Nadine Rae Leavell, Monique E Muggli, Richard D Hurt, James Repace

Do doctors who volunteer their services in disasters overseas do more harm than good?
Hasan Tahir, Zafar Iqbal

Prostitution shake-up
one sex worker's view

January 21
Intrapleural streptokinase for pleural infection
Demosthenes Bouros, Katerina M Antoniou, Richard W Light

Treatment of rheumatoid arthritis
Paul Emery

Pulmonary embolism in hospital practice
Grace V Robinson


January 14

When to test women for human papillomavirus
Mark Schiffman, Philip E Castle

Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studies
Rachel Huxley, Federica Barzi, Mark Woodward

Gastro-oesophageal reflux disease
Mark Fox, Ian Forgacs

January 7
Fundoscopy: to dilate or not to dilate?
Gerald Liew, Paul Mitchell, Jie Jin Wang, Tien Yin Wong

Magnet therapy
Leonard Finegold, Bruce L Flamm

Use of a dummy (pacifier) during sleep and risk of sudden infant death syndrome (SIDS): population based case-control study
De-Kun Li, Marian Willinger, Diana B Petitti, Roxana Odouli, Liyan Liu, Howard J Hoffman

Recent advances in the diagnosis and management of migraine
Peter J Goadsby